Precursors of ovarian cancer in the fallopian tube: Serous tubal intraepithelial carcinoma - an update

被引：29

作者：

Zeppernick, Felix ^{[1
,2
,4
]}

Meinhold-Heerlein, Ivo ^{[4
]}

Shih, Ie-Ming ^{[1
,2
,3
]}

机构：

[1] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21205 USA

[2] Johns Hopkins Med Inst, Dept Gynecol & Obstet, Baltimore, MD 21205 USA

[3] Johns Hopkins Med Inst, Dept Oncol, Baltimore, MD 21205 USA

[4] Univ Hosp Aachen, Dept Gynecol & Obstet, Aachen, Germany

来源：

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | 2015年 / 41卷 / 01期

关键词：

epithelial ovarian cancer; fallopian tube; high-grade serous carcinoma; precursor; serous tubal intraepithelial carcinoma; SALPINGO-OOPHORECTOMY; RISK; WOMEN; BRCA1; CARRIERS; MODEL; HYSTERECTOMY; HYPOTHESIS; MUTATIONS; NEOPLASIA;

D O I：

10.1111/jog.12550

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of serous tubal intraepithelial carcinoma', which is believed to represent the precursor lesion in high-grade serous ovarian carcinoma. In this review, lines of evidence for this are discussed and possible future implications for clinical and research settings are outlined.

引用

页码：6 / 11

页数：6

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