Genetic endowments, parental resources and adult health: Evidence from the Young Finns Study

被引:2
|
作者
Pehkonen, Jaakko [1 ]
Viinikainen, Jutta [1 ]
Bockerman, Petri [2 ]
Lehtimaki, Terho [3 ,4 ]
Pitkanen, Niina [3 ,4 ]
Raitakari, Oi [5 ,6 ]
机构
[1] Univ Jyvaskyla, Sch Business & Econ, Jyvaskyla, Finland
[2] IZA, Labour Inst Econ Res, Turku Sch Econ, Helsinki, Finland
[3] Univ Tampere, Fimlab Labs, Dept Clin Chem, Tampere, Finland
[4] Univ Tampere, Fac Med & Life Sci, Tampere, Finland
[5] Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku, Finland
[6] Turku Univ Hosp, Dept Clin Physiol & Nucl Med, Turku, Finland
基金
芬兰科学院;
关键词
Genetic risk scores; Biomarkers; Adult health; Parental resources; Genome-wide association studies; CARDIOVASCULAR RISK-FACTORS; ENVIRONMENT INTERACTIONS; SOCIOECONOMIC INEQUALITIES; EDUCATIONAL-ATTAINMENT; LABOR-MARKET; CHILDHOOD; VARIANTS; OUTCOMES; ASSOCIATIONS; EXPECTANCY;
D O I
10.1016/j.socscimed.2017.04.030
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This paper uses longitudinal survey data linked to administrative registers to examine socioeconomic gradients in health, particularly whether the effects of genetic endowments interact with the socioeconomic resources of the parental household. We find that genetic risk scores contribute to adult health measured by biomarkers. This result is consistent with the findings from genome-wide association studies. Socioeconomic gradients in health differ based on biomarker and resource measures. Family education is negatively related to obesity and the waist-hip ratio, and family income is negatively related to low-density lipoprotein cholesterol and triglyceride levels. Parental resources do not modify the effects of genetic endowment on adult health. However, there is evidence for gene-family income interactions for triglyceride levels, particularly among women. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:191 / 200
页数:10
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