Prostate cancer: from Gleason scoring to prognostic grade grouping

被引:29
|
作者
Montironi, Rodolfo [1 ]
Santoni, Matteo [2 ]
Mazzucchelli, Roberta [1 ]
Burattini, Luciano [2 ]
Berardi, Rossana [2 ]
Galosi, Andrea B. [3 ]
Cheng, Liang [4 ]
Lopez-Beltran, Antonio [5 ]
Briganti, Alberto [6 ]
Montorsi, Francesco [6 ]
Scarpelli, Marina [1 ]
机构
[1] Polytech Univ Marche Reg, United Hosp, Sch Med, Sect Pathol Anat, I-60126 Ancona, Italy
[2] Polytech Univ Marche Reg, AOU Osped Riuniti, Clin Oncol Med, I-60126 Ancona, Italy
[3] Polytech Univ Marche Reg, Sch Med, Urol Clin, I-60126 Ancona, Italy
[4] Indiana Univ Sch Med, Dept Pathol & Lab Med, Indianapolis, IN 46202 USA
[5] Champalimaud Clin Ctr, Pathol Serv, Lisbon, Portugal
[6] IRCCS, Osped San Raffaele, URI, Unit Urol,Div Oncol, Milan, Italy
关键词
prognostic grade grouping; 2014 ISUP Gleason modified system; International society of urological pathology; Prostate cancer; Gleason grading; 2005 ISUP Gleason modified system; 2014 INTERNATIONAL SOCIETY; ISUP CONSENSUS CONFERENCE; NEEDLE-BIOPSY; PATHOLOGY; CARCINOMA; ADENOCARCINOMA; MEN; METASTASIS; SYSTEM;
D O I
10.1586/14737140.2016.1160780
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The Gleason grading system was developed in the late 1960s by Dr. Donald F. Gleason. Due to changes in prostatic adenocarcinoma (PAC) detection and treatment, newer technologies to better characterize prostatic pathology, subsequently described variants of PAC and further data relating various morphologic patterns to prognosis, the application of the Gleason grading system changed substantially in surgical pathology. First in 2005 and more recently in 2014, consensus conferences were held to update PAC grading. Here, we review of the successive changes in the grading of PAC from the original system, with emphasis on the newest prognostic grade grouping.
引用
收藏
页码:433 / 440
页数:8
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