Investigation of the site of precursors for IgA-producing cells in the chicken intestine

被引：14

作者：

Muir, WI ^{[1
]}

Bryden, WL

Husband, AJ

机构：

[1] Univ Sydney, Fac Vet Sci, Dept Vet Anat & Pathol, Sydney, NSW 2006, Australia

[2] Univ Sydney, Fac Vet Sci, Dept Anim Sci, Sydney, NSW 2006, Australia

来源：

IMMUNOLOGY AND CELL BIOLOGY | 2000年 / 78卷 / 03期

关键词：

adoptive cell transfer; avian intestinal immunity; B cell; bursectomy; immunoglobulin A;

D O I：

10.1046/j.1440-1711.2000.00915.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Bursectomized chicks received lymphocyte single cell suspensions harvested from the bursa of Fabricius (BF), ileal lymphoid aggregate (ILA), caecal tonsils (CT), spleen and peripheral blood. Four days after cell transfer, repopulation of the duodenal and CT lamina propria in age-matched recipient bursectomized chickens with IgA-secreting plasma cells was determined. The results indicate the highest level of reconstitution with cells derived from BE but substantial numbers of IgA-secreting plasma cells were also observed in a number of birds that received lymphocytes originating from the ILA and CT.

引用

页码：294 / 296

页数：3

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