Pregnancy Is a Risk Factor for Secondary Focal Segmental Glomerulosclerosis in Women with a History of Very Low Birth Weight

被引:5
|
作者
Tanaka, Mari [1 ]
Iwanari, Sachio [1 ]
Tsujimoto, Yasushi [2 ]
Taniguchi, Keisuke [1 ]
Hagihara, Koichiro [1 ]
Fumihara, Daiki [1 ]
Miki, Syo [1 ]
Shimoda, Saeko [1 ]
Ikeda, Masaki [1 ]
Takeoka, Hiroya [1 ]
机构
[1] Hyogo Prefectural Amagasaki Gen Med Ctr, Dept Nephrol & Dialysis, Amagasaki, Hyogo, Japan
[2] Kyoto Univ, Grad Sch Med & Publ Hlth, Dept Healthcare Epidemiol, Kyoto, Japan
关键词
low birth weight; focal segmental glomerulosclerosis; post-adaptive; pregnancy; glomerular hyperfiltration; two-hit theory; PRETERM BIRTH; PREECLAMPSIA; DISEASE; PROGRESSION; CHILDREN; OBESITY; KIDNEY; NUMBER; SIZE;
D O I
10.2169/internalmedicine.56.8032
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Low birth weight (LBW) has been known to increase the susceptibility to renal injury in adulthood. A 26-year-old woman developed proteinuria in early pregnancy; she had been born with very LBW. The clinical course was progressive, and an emergency Caesarean section was performed at 36 weeks due to acute kidney injury. A renal biopsy provided a diagnosis of post-adaptive focal segmental glomerulosclerosis. Increased demand for glomerular filtration during early pregnancy appeared to have initiated the renal injury. This report highlights the fact that pregnancy might be a risk factor for renal injury in women born with LBW.
引用
收藏
页码:1537 / 1541
页数:5
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