Pregnancy Is a Risk Factor for Secondary Focal Segmental Glomerulosclerosis in Women with a History of Very Low Birth Weight

被引：5

作者：

Tanaka, Mari ^{[1
]}

Iwanari, Sachio ^{[1
]}

Tsujimoto, Yasushi ^{[2
]}

Taniguchi, Keisuke ^{[1
]}

Hagihara, Koichiro ^{[1
]}

Fumihara, Daiki ^{[1
]}

Miki, Syo ^{[1
]}

Shimoda, Saeko ^{[1
]}

Ikeda, Masaki ^{[1
]}

Takeoka, Hiroya ^{[1
]}

机构：

[1] Hyogo Prefectural Amagasaki Gen Med Ctr, Dept Nephrol & Dialysis, Amagasaki, Hyogo, Japan

[2] Kyoto Univ, Grad Sch Med & Publ Hlth, Dept Healthcare Epidemiol, Kyoto, Japan

来源：

INTERNAL MEDICINE | 2017年 / 56卷 / 12期

关键词：

low birth weight; focal segmental glomerulosclerosis; post-adaptive; pregnancy; glomerular hyperfiltration; two-hit theory; PRETERM BIRTH; PREECLAMPSIA; DISEASE; PROGRESSION; CHILDREN; OBESITY; KIDNEY; NUMBER; SIZE;

D O I：

10.2169/internalmedicine.56.8032

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Low birth weight (LBW) has been known to increase the susceptibility to renal injury in adulthood. A 26-year-old woman developed proteinuria in early pregnancy; she had been born with very LBW. The clinical course was progressive, and an emergency Caesarean section was performed at 36 weeks due to acute kidney injury. A renal biopsy provided a diagnosis of post-adaptive focal segmental glomerulosclerosis. Increased demand for glomerular filtration during early pregnancy appeared to have initiated the renal injury. This report highlights the fact that pregnancy might be a risk factor for renal injury in women born with LBW.

引用

页码：1537 / 1541

页数：5

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