Synthesis of 1,1-bis(1,2,4-triazol-1-yl)-based potential aromatase inhibitors

被引:1
|
作者
Katritzky, AR [1 ]
Pastor, A [1 ]
Voronkov, MV [1 ]
机构
[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA
关键词
D O I
10.1002/jhet.5570370412
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reactions of bis-(1,2,4-triazolyl) sulfoxide 2 with various carbonyl compounds 3 led to the formation of twelve corresponding I,1-bis-(1,2,4-triazolyl) compounds, with structures resembling closely some previously prepared aromatase inhibitors.
引用
收藏
页码:743 / 745
页数:3
相关论文
共 50 条
  • [21] 1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethanone
    Guven, Ozden Ozel
    Tahtaci, Hakan
    Coles, Simon J.
    Hokelek, Tuncer
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1604 - U3253
  • [22] ALKYLATION OF 1-ARYL-1-(1,2,4-TRIAZOL-1-YL)-2-PROPANONES
    EHRHARDT, H
    HANDTE, R
    LIEBIGS ANNALEN DER CHEMIE, 1985, (05): : 1088 - 1092
  • [23] 1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethanol
    Guven, Ozden Ozel
    Tahtaci, Hakan
    Coles, Simon J.
    Hokelek, Tuncer
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1254 - U1822
  • [24] 4-(1H-1,2,4-triazol-1-yl)phenol
    Foces-Foces, C
    Cabildo, P
    Claramunt, RM
    Elguero, J
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 1999, 55 : 1160 - 1163
  • [25] 4-(1H-1,2,4-Triazol-1-yl)phenol
    Foces-Foces, C.
    Cabildo, P.
    Claramunt, R.M.
    Elguero, J.
    Acta Crystallographica, Section C: Crystal Structure Communications, 1999, 55 (07): : 1160 - 1163
  • [26] Poly[bis[μ2-2-(1H-1,2,4-triazol-1-yl)acetato]zinc(II)]
    Xie, Li-xia
    Tong, Yan
    Li, Xin
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : M1315 - U687
  • [27] Synthesis and Biological Activities of ω-Heterocyclyl-ω-(1H-1,2,4-triazol-1-yl) Acetophenones
    Chang Hu CHU
    Xiao Wen SUN
    Zi Yi ZHANG
    Zhi Chun LI
    Ren An LIAO(Department of Chemistry
    Chinese Chemical Letters, 1999, (05) : 361 - 364
  • [28] Synthesis and biological activities of ω-heterocyclyl-ω-(1H-1,2,4-triazol-1-yl) acetophenones
    Chu, CH
    Sun, XW
    Zhang, ZY
    Li, ZC
    Liao, RA
    CHINESE CHEMICAL LETTERS, 1999, 10 (05) : 361 - 364
  • [29] 2-benzoyl-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide and 2-(4-methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide
    Jian, FF
    Xiao, HL
    Qin, YQ
    Xu, LZ
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2004, 60 : O492 - O493
  • [30] Effect of anions on architectures of transition metal complexes with 1,4-bis (1,2,4-triazol-1-yl)butane
    Li, Xia
    Gu, Ya-Kun
    Deng, Xue-Bin
    Zhao, Kai
    Jin, Lin-Pei
    CRYSTENGCOMM, 2011, 13 (22) : 6665 - 6673