Normalization of diabetic wound healing

被引：20
|
作者：
Francis-Goforth, Kellie N. [2 ]
Harken, Alden H. [2 ]
Saba, Julie D. [1 ]
机构：
[1] Childrens Hosp, Oakland Res Inst, Canc Biol Lab, Oakland, CA 94609 USA
[2] Univ Calif San Francisco E Bay, Dept Gen Surg, San Francisco, CA USA
来源：
SURGERY | 2010年 / 147卷 / 03期
基金：
美国国家卫生研究院;
关键词：
SPHINGOSINE; 1-PHOSPHATE; SPHINGOSINE-1-PHOSPHATE; GROWTH; ANGIOGENESIS; FIBROBLAST; RECEPTOR;
D O I：
10.1016/j.surg.2009.04.038
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Hypothesis: Impaired wound healing in diabetics is due to pathologic angiogenesis, which is a result of aberrant sphingosine-1-phosphate signaling. Pharmacologic modulation of sphingosine-1-phosphate-dependent signaling normalizes healing in diabetic wounds. © 2010 Mosby, Inc. All rights reserved.
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页码：446 / 449
页数：4
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