Avian Influenza-DNA Hybridization Detection using Wavelength Interrogation-based Surface Plasmon Resonance Biosensor

被引：0

作者：

Kim, Shin Ae ^{[1
]}

Kim, Sung June ^{[1
]}

Byun, Kraig Min ^{[2
]}

Lee, Sang Hun ^{[3
]}

Park, Tai Hyun ^{[3
]}

Kim, Sung Guk ^{[4
]}

Shuler, Michael L. ^{[5
]}

机构：

[1] Seoul Natl Univ, Sch Elect Engn & Comp Sci, Seoul, South Korea

[2] Kyung Hee Univ, Dept Biomed Engn, Yongin, South Korea

[3] Seoul Natl Univ, Sch Chem & Biol Engn, Seoul, South Korea

[4] Cornell Univ, Coll Vet Med, Ithaca, NY USA

[5] Cornell Univ, Dept Biomed Engn, Ithaca, NY USA

来源：

2009 IEEE SENSORS, VOLS 1-3 | 2009年

关键词：

PERIODIC METALLIC NANOWIRES; SENSITIVITY ENHANCEMENT; GOLD;

D O I：

10.1109/ICSENS.2009.5398267

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A wavelength interrogation-based surface plasmon resonance (SPR) biosensor has been investigated for a detection of avian influenza DNA (AI-DNA). The hybridization reaction between AI-DNA and the immobilized oligonucleotide probe on a gold surface was monitored. The results showed that SPR biosensor can provide a linear detection suitable for quantification of AI-DNA hybridization as well as a large dynamic range. The experimental results were consistent well with numerical calculations using rigorous-coupled-wave analysis (RCWA). This study demonstrates the potential of using wavelength-scanning type SPR biosensor in a simple and real-time detection of AI virus.

引用

页码：832 / +

页数：2

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