Tracer kinetic analysis of the SV2A ligand 11C-UCBA as a PET marker for synaptic density in humans

被引:0
|
作者
Lubberink, Mark [1 ]
Appel, Lieuwe [1 ]
Gaging, Johannes [1 ]
Lindskog, Karolina [1 ]
Danfors, Torsten [1 ]
Larsson, Elna-Marie [1 ]
Kumlien, Eva [1 ]
Antoni, Gunnar [1 ]
机构
[1] Uppsala Univ, Uppsala, Sweden
关键词
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
631
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Drug characteristics derived from kinetic modeling: combined 11C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A
    Naganawa, Mika
    Gallezot, Jean-Dominique
    Finnema, Sjoerd J.
    Maguire, Ralph Paul
    Mercier, Joel
    Nabulsi, Nabeel B.
    Kervyn, Sophie
    Henry, Shannan
    Nicolas, Jean-Marie
    Huang, Yiyun
    Chen, Ming-Kai
    Hannestad, Jonas
    Klitgaard, Henrik
    Stockis, Armel
    Carson, Richard E.
    EJNMMI RESEARCH, 2022, 12 (01)
  • [32] Kinetic modeling of CB1 PET tracer [11C]OMAR in rhesus monkeys and humans
    Normandin, Marc
    Weinzimmer, David
    Ropchan, Jim
    Labaree, David
    Lin, Kuo-Shyan
    Mason, Neale
    Carson, Richard
    D'Souza, Deepak
    Neumeister, Alexander
    Huang, Yiyun
    JOURNAL OF NUCLEAR MEDICINE, 2010, 51
  • [33] [11C]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A
    Estrada, Sergio
    Lubberink, Mark
    Thibblin, Alf
    Sprycha, Margareta
    Buchanan, Tim
    Mestdagh, Nathalie
    Kenda, Benoit
    Mercier, Joel
    Provins, Laurent
    Gillard, Michel
    Tytgat, Dominique
    Antoni, Gunnar
    NUCLEAR MEDICINE AND BIOLOGY, 2016, 43 (06) : 325 - 332
  • [34] Imaging Brain SV2A Density Measured With [11 C]UCB-J mu PET as a Readout Of Depression and Antidepressant Response in a Mouse Model of Depression
    Leroy, Claire
    Goutal, Sebastien
    David, Denis
    Saba, Wadad
    Goislard, Maud
    Bottlaender, Michel
    Caille, Fabien
    Nguyen, Phi T.
    Gardier, Alain
    Hen, Rene
    Corruble, Emmanuelle
    Colle, Romain
    Tournier, Nicolas
    Mendez-David, Indira
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 (SUPPL 1) : 252 - 253
  • [35] Tracer kinetic modeling of [11C]JNJ42491293, a PET ligand for the mGluR2 receptor in the human brain
    Koole, Michel
    Bormans, Guy
    De Hoon, Jan
    Derdelinckx, Inge
    Langlois, Xavier
    Celen, Sofie
    Verbruggen, Alfons
    Ignacio Andres, Jose
    Schmidt, Mark
    Van Laere, Koen
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2012, 32 : S28 - S29
  • [36] The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study
    Ellis Chika Onwordi
    Thomas Whitehurst
    Ayla Mansur
    Ben Statton
    Alaine Berry
    Marina Quinlan
    Declan P. O’Regan
    Maria Rogdaki
    Tiago Reis Marques
    Eugenii A. Rabiner
    Roger N. Gunn
    Anthony C. Vernon
    Sridhar Natesan
    Oliver D. Howes
    Translational Psychiatry, 11
  • [37] The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study
    Onwordi, Ellis Chika
    Whitehurst, Thomas
    Mansur, Ayla
    Statton, Ben
    Berry, Alaine
    Quinlan, Marina
    O'Regan, Declan P.
    Rogdaki, Maria
    Marques, Tiago Reis
    Rabiner, Eugenii A.
    Gunn, Roger N.
    Vernon, Anthony C.
    Natesan, Sridhar
    Howes, Oliver D.
    TRANSLATIONAL PSYCHIATRY, 2021, 11 (01)
  • [38] Longitudinal test-retest reproducibility of 11C-UCB-J, a PET tracer for synaptic density imaging
    Khattar, Nikkita
    Naganawa, Mika
    Gallezot, Jean-Dominique
    Mondal, Jayanta
    Lu, Yihuan
    Rossano, Samantha
    Matuskey, David
    Huang, Yiyun H.
    Carson, Richard E.
    Toyonaga, Takuya
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021, 41 (1_SUPPL): : 162 - 163
  • [39] Optimizing OSEM reconstruction parameters for imaging synaptic density in humans with 11C-UCB-J PET
    Rossano, Samantha
    Finnema, Sjoerd
    Fontaine, Kathryn
    Carson, Richard
    JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [40] Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue
    Koole, Michel
    van Aalst, June
    Devrome, Martijn
    Mertens, Nathalie
    Serdons, Kim
    Lacroix, Brigitte
    Mercier, Joel
    Sciberras, David
    Maguire, Paul
    Van Laere, Koen
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2019, 46 (02) : 396 - 406