Pharmacological modulation of CXCL12-CXCR4 intracellular trafficking potentiates the in vitro and in vivo activity of the BET bromodomain inhibitor CPI203 in diffuse large B-cell lymphoma

被引:1
|
作者
Recasens-Zorzo, Clara
Cardesa-Salzmann, Teresa
Ros-Blanco, Laia
Esteve-Arenys, Anna
Clot, Guillem
Guerrero-Hernandez, Martina
Valera, Alejandra
Moros, Alejandra
Gutierrez, Gonzalo
Casanova, Isolda
Mangues, Ramon
Sanjuan, Alejandra
Menendez, Pablo
Rodriguez, Vanina
Martinez, Antonio
Jares, Pedro
Colomer, Dolors
Teixido, Jordi
Borrell, Jose Ignacio
Campo, Elias
Lopez-Guillermo, Armando
Colomo, Luis
Perez-Galan, Patricia
Roue, Gael
机构
关键词
D O I
10.1158/1538-7445.AM2017-2169
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2169
引用
收藏
页数:2
相关论文
共 7 条
  • [1] Pharmacological modulation of CXCR4 cooperates with BET bromodomain inhibition in diffuse large B-cell lymphoma
    Recasens-Zorzo, Clara
    Cardesa-Salzmann, Teresa
    Petazzi, Paolo
    Ros-Blanco, Laia
    Esteve-Arenys, Anna
    Clot, Guillem
    Guerrero-Hernandez, Martina
    Rodriguez, Vanina
    Soldini, Davide
    Valera, Alexandra
    Moros, Alexandra
    Climent, Fina
    Gonzalez-Barca, Eva
    Mercadal, Santiago
    Arenillas, Leonor
    Calvo, Xavier
    Mate, Jose Luis
    Gutierrez-Garcia, Gonzalo
    Casanova, Isolda
    Mangues, Ramon
    Sanjuan-Pla, Alejandra
    Bueno, Clara
    Menendez, Pablo
    Martinez, Antonio
    Colomer, Dolors
    Estrada Tejedor, Roger
    Teixido, Jordi
    Campo, Elias
    Lopez-Guillermo, Armando
    Ignacio Borrell, Jose
    Colomo, Luis
    Perez-Galan, Patricia
    Roue, Gael
    [J]. HAEMATOLOGICA, 2019, 104 (04) : 778 - 788
  • [2] The BET bromodomain inhibitor (BET-i) BAY 1238097: Mechanism of action and pre-clinical activity in diffuse large B-cell lymphoma (DLBCL)
    Bernasconi, E.
    Gaudio, E.
    Lejeune, P.
    Tarantelli, C.
    Rinaldi, A.
    Kwee, I.
    Mensah, A. A.
    Chung, E. Y. L.
    Stathis, A.
    Ocker, M.
    Zucca, E.
    Haendler, B.
    Bertoni, F.
    [J]. EUROPEAN JOURNAL OF CANCER, 2016, 69 : S84 - S84
  • [3] Tyrosine Kinase Inhibitor Si409 Has In Vitro and In Vivo Anti-Tumor Activity Against Diffuse Large B-Cell Lymphoma
    Rango, Enrico
    Di Maria, Salvatore
    Zamperini, Claudio
    Poggialini, Federica
    Crespan, Emmanuele
    Perini, Cecilia
    Sabetta, Samantha
    Saponara, Simona
    Fusi, Fabio
    Maga, Giovanni
    Angelucci, Adriano
    Gaudio, Eugenio
    Berton, Francesco
    Schenone, Silvia
    Botta, Lorenzo
    Dreassi, Elena
    Botta, Maurizio
    [J]. PHARMACEUTICAL CHEMISTRY JOURNAL, 2023, 56 (12) : 1616 - 1626
  • [4] Tyrosine Kinase Inhibitor Si409 Has In Vitro and In Vivo Anti-Tumor Activity Against Diffuse Large B-Cell Lymphoma
    Enrico Rango
    Salvatore Di Maria
    Claudio Zamperini
    Federica Poggialini
    Emmanuele Crespan
    Cecilia Perini
    Samantha Sabetta
    Simona Saponara
    Fabio Fusi
    Giovanni Maga
    Adriano Angelucci
    Eugenio Gaudio
    Francesco Berton
    Silvia Schenone
    Lorenzo Botta
    Elena Dreassi
    Maurizio Botta
    [J]. Pharmaceutical Chemistry Journal, 2023, 56 : 1616 - 1626
  • [5] The BET Inhibitor OTX015 (MK-8628) Shows in Vivo Antitumor Activity in Combination with Additional Targeted Agents in Diffuse Large B-Cell Lymphoma (DLBCL)
    Gaudio, Eugenio
    Cascione, Luciano
    Ponzoni, Maurilio
    Tarantelli, Chiara
    Bernasconi, Elena
    Riveiro, Maria Eugenia
    Cvitkovic, Esteban
    Zucca, Emanuele
    Bertoni, Francesco
    [J]. BLOOD, 2015, 126 (23)
  • [6] The Novel Kinesin Spindle Protein Inhibitor SB-743921 Exhibits Marked Activity In In Vivo and In Vitro In Models of Aggressive Diffuse Large B-Cell Lymphoma
    Bongero, Danielle C.
    Paoluzzi, Luca
    Marchi, Enrica
    Roberto, Neisa
    Escandon, Rafael
    Wood, Ken
    O'Connor, Owen A.
    [J]. BLOOD, 2010, 116 (21) : 58 - 58
  • [7] TAS-5567, a highly potent and selective inhibitor of SYK kinase, demonstrated antitumor activity in diffuse large B-cell lymphoma (DLBCL) cellsin vitro and in vivo
    Irie, Hiroki
    Kawagishi, Aki
    Ishihara, Keiko
    Tsuji, Shingo
    Nakatsuru, Yoko
    Kuze, Jiro
    Fujino, Naoko
    Ogino, Yoshio
    Komatani, Hideya
    Utsugi, Teruhiro
    [J]. MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)