Anti-PL-7 Antisynthetase Syndrome with Eosinophilic Pleural Effusion

被引：10

作者：

Saito, Go ^{[1
]}

Kono, Masato ^{[1
]}

Tsutsumi, Akari ^{[1
]}

Koyanagi, Yu ^{[1
]}

Miyashita, Koichi ^{[1
]}

Kobayashi, Takeshi ^{[1
]}

Hozumi, Hironao ^{[2
]}

Miki, Yoshihiro ^{[1
]}

Arai, Yoshifumi ^{[3
]}

Otsuki, Yoshiro ^{[3
]}

Hashimoto, Dai ^{[1
]}

Fujisawa, Tomoyuki ^{[2
]}

Nakamura, Toru ^{[4
]}

Suda, Takafumi ^{[2
]}

Nakamura, Hidenori ^{[1
]}

机构：

[1] Seirei Hamamatsu Gen Hosp Japan, Dept Pulm Med, Hamamatsu, Shizuoka, Japan

[2] Hamamatsu Univ Sch Med, Dept Internal Med, Div 2, Hamamatsu, Shizuoka, Japan

[3] Seirei Hamamatsu Gen Hosp, Dept Pathol, Hamamatsu, Shizuoka, Japan

[4] Seirei Hamamatsu Gen Hosp, Dept Gen Thorac Surg, Hamamatsu, Shizuoka, Japan

来源：

INTERNAL MEDICINE | 2018年 / 57卷 / 15期

基金：

日本学术振兴会;

关键词：

antisynthetase syndrome (ASS); aminoacyl-tRNA synthetase (ARS); anti-PL-7; antibody; eosinophilic pleural effusion (EPE); dermatomyositis (DM); INTERSTITIAL LUNG-DISEASE; CLINICAL-MANIFESTATIONS; JAPANESE PATIENTS; POSITIVE PATIENTS; AUTOANTIBODIES; POLYMYOSITIS/DERMATOMYOSITIS; DERMATOMYOSITIS; POLYMYOSITIS; INVOLVEMENT; ANTIBODIES;

D O I：

10.2169/internalmedicine.0302-17

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 68-year-old woman was admitted to our hospital with fever and pleural effusion. Her thoracentesis showed eosinophilic pleural effusion (EPE) without any evidence of malignancy, infection, or trauma. Pleural biopsy revealed pleuritis and intercostal myositis. Characteristic skin manifestations, including Gottron's sign, interstitial lung disease, and pericardial effusion, appeared later in the clinical course. She was finally diagnosed with anti-PL-7 antisynthetase syndrome (ASS) based on the presence of anti-PL-7 antibody, and she fulfilled the diagnostic criteria for dermatomyositis. These clinical manifestations improved with immunosuppressive therapy. EPE might therefore be one of the characteristic features of anti-PL-7 ASS.

引用

页码：2227 / 2232

页数：6

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