Synthesis and characterization of nanobelt-shaped Na, F and carbonate multi-substituted hydroxyapatite

Na, F and carbonate multi-substituted hydroxyapatite (NFCH) with nanobelt shape has been synthesized using a combined method of ultrasound-assisted electrochemical deposition and ion exchange. The morphology, microstructure and in-vitro bioactivity of the NFCH are analyzed. The results show that the nanobelt-shaped NFCH are 5-40 nm in thickness, 250-700 nm in width and tens of micrometers in length. The nanobelt-shaped NFCH is oriented randomly and interlocked with each other on carbon/ carbon composite substrates. The nanobelt-shaped NFCH could induce the precipitation of apatite layers with Ca/P molar ratios of 1.34-1.51 on its surface in simulated body fluid, exhibiting excellent in-vitro biocompatibility. The nanobelt-shaped NFCH should have potential application as reinforcement phase for bioactive coatings or as scaffold for tissue engineering. (C) 2014 Elsevier B.V. All rights reserved.