The use of antisence oligonucleotides for modulation of cytokine gene expression.

被引：0
|
作者：
Kozlov, VA [1 ]
Sennikov, SV [1 ]
机构：
[1] Russian Acad Med Sci, Inst Clin Immunol, Siberian Branch, Novosibirsk 630099, Russia
来源：
VOPROSY MEDITSINSKOI KHIMII | 1997年 / 43卷 / 05期
关键词：
antisense oligonucleotides; modulation of cytokine gene expression; haemopoesis; immunopoesis;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The review summarizes literature data on the mechanism of action and the use of antisence oligonucleotides for modulation of cytokine gene expression in haemo- and immunopoesis. This new approach for gene-directed modulation of the gene expression allows to analyze both intercellular and intracellular protein interaction. Use of this approach is prospective for both experimental researches in vivo and in vitro and application in therapeutic purposes.
引用
收藏
页码：308 / 320
页数：13
相关论文
共 50 条
  • [1] Effects of a chimeric cytokine, progenipoietin, on apoptosis and gene expression.
    Navolanic, PM
    McCubrey, JA
    Saleh, OA
    Pearce, ML
    Blalock, WL
    Steelman, LS
    Burrows, CJ
    Franklin, RA
    Doshi, PD
    McKearn, JP
    [J]. BLOOD, 2000, 96 (11) : 83A - 83A
  • [2] Modulation of Gene Expression in the Eye with Antisense Oligonucleotides
    Hu, Jiaxin
    Gong, Xin
    Fan, Yan
    Aguilar, Selina
    Rigo, Frank
    Prakash, Thahza P.
    Corey, David R.
    Mootha, V. Vinod
    [J]. NUCLEIC ACID THERAPEUTICS, 2023, 33 (06) : 339 - 347
  • [3] Modulation of cytokine gene expression by curcumin
    Chan, MMY
    Huang, HI
    Mattiacci, JA
    Fong, D
    [J]. FOOD FACTORS IN HEALTH PROMOTION AND DISEASE PREVENTION, 2003, 851 : 86 - 99
  • [4] Cytokine effects upon osteoclastogenesis and cathepsin K gene expression.
    Corisdeo, S
    Gyda, M
    Troen, BR
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2001, 49 (04) : S46 - S46
  • [5] Cytokine effects upon osteoclastogenesis and cathepsin K gene expression.
    Corisdeo, S
    Gyda, M
    Troen, BR
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 : S385 - S385
  • [6] Modulation of cytokine gene expression by curcumin.
    Chan, MM
    Huang, HI
    Fong, D
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U26 - U26
  • [7] Essential role for annexin I in the regulation of proinflammatory cytokine gene expression.
    Yang, YH
    Toh, ML
    Hall, P
    Leech, M
    Croxtall, J
    Flower, R
    Morand, EF
    [J]. ARTHRITIS AND RHEUMATISM, 2003, 48 (09): : S478 - S478
  • [8] MODULATION OF CYTOKINE GENE-EXPRESSION BY NEUROPEPTIDES
    NAIR, MPN
    GAMLIEL, E
    LOMAX, M
    KWAK, SP
    RISER, BL
    KRONFOL, ZA
    SCHWARTZ, SA
    [J]. CLINICAL RESEARCH, 1990, 38 (03): : A853 - A853
  • [9] Comparison of RNA preparation methods and their effect on cytokine/chemokine gene expression.
    Asare, AL
    Kolchinsky, SA
    Wood, P
    Seyfert-Margolis, VL
    [J]. CLINICAL IMMUNOLOGY, 2005, 115 : S207 - S208
  • [10] Modulation of psoriasis-related gene expression by antisense oligonucleotides
    Wingens, M
    vanHooijdonk, CAEM
    Schalkwijk, J
    vanErp, PEJ
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1997, 109 (03) : 443 - 443
12345