A two-step synthesis of hexahydropyrrolo[1,2-d][1,2,4]triazine-1,4-dione and related compounds

被引：7
|
作者：
Obreza, A [1 ]
Urleb, U [1 ]
机构：
[1] Lek DD, Ljubljana, Slovenia
来源：
SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 06期
关键词：
hexahydropyrrolo[1,2-d][1,2,4]triazine-1, 4-dione; synthesis; proline mimetics;
D O I：
10.1081/SCC-120016366
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of tert-butyl 1-hydrazinecarboxylate with triphosgene and ethyl 2-pyrrolidinecarboxylate or related compounds, followed by the removal of the Boc-protecting group with gaseous hydrogen chloride in anhydrous acetic acid, yields hexahydropyrrolo [1,2-d][1,2,4]triazine-1,4-dione and related heterocycles.
引用
收藏
页码：1011 / 1018
页数：8
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