A two-step synthesis of hexahydropyrrolo[1,2-d][1,2,4]triazine-1,4-dione and related compounds

被引：7

作者：

Obreza, A ^{[1
]}

Urleb, U ^{[1
]}

机构：

[1] Lek DD, Ljubljana, Slovenia

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 06期

关键词：

hexahydropyrrolo[1,2-d][1,2,4]triazine-1, 4-dione; synthesis; proline mimetics;

D O I：

10.1081/SCC-120016366

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of tert-butyl 1-hydrazinecarboxylate with triphosgene and ethyl 2-pyrrolidinecarboxylate or related compounds, followed by the removal of the Boc-protecting group with gaseous hydrogen chloride in anhydrous acetic acid, yields hexahydropyrrolo [1,2-d][1,2,4]triazine-1,4-dione and related heterocycles.

引用

页码：1011 / 1018

页数：8

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