Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions

被引：38
|
作者：
Yoon, Kunsang [1 ]
Goyal, Poorva [1 ]
Weck, Marcus [1 ]
机构：
[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA
来源：
ORGANIC LETTERS | 2007年 / 9卷 / 11期
关键词：
D O I：
10.1021/ol062949h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Monofunctionalized polyamide-based dendrimers containing either a terminal azide or alkyne moiety have been designed and synthesized via a convergent synthetic approach. The monofunctionalization allows for the single attachment of a functional moiety in quantitative yields by using 1,3-dipolar cycloadditions, thereby opening the possibility for targeted dendrimer functionalization.
引用
收藏
页码：2051 / 2054
页数：4
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