Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

被引：168
|
作者：
Vezzoli, Alessandro [1 ]
Bonadies, Nicolas [2 ]
Allen, Mark D. [1 ]
Freund, Stefan M. V. [3 ]
Santiveri, Clara M. [1 ]
Kvinlaug, Brynn T. [2 ]
Huntly, Brian J. P. [2 ]
Goettgens, Berthold [2 ]
Bycroft, Mark [1 ]
机构：
[1] MRC, Ctr Prot Engn, Cambridge, England
[2] Univ Cambridge, Cambridge Inst Med Res, Dept Haematol, Cambridge, England
[3] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2010年 / 17卷 / 05期
基金：
英国医学研究理事会;
关键词：
BINDING MODULES; STEM-CELLS; CHROMATIN; PROTEIN; METHYLATION; FAMILY;
D O I：
10.1038/nsmb.1797
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Trimethylation of Lys36 in histone H3 (H3K36me3) coordinates events associated with the elongation phase of transcription and is also emerging as an important epigenetic regulator of cell growth and differentiation. We have identified the PWWP domain of bromo and plant homeodomain (PHD) finger-containing protein 1 (BRPF1) as a H3K36me3 binding module and have determined the structure of this domain in complex with an H3K36me3-derived peptide.
引用
收藏
页码：617 / 619
页数：3
相关论文
共 50 条
  • [31] H3K36me3, message from chromatin to DNA damage repair
    Zhongxing Sun
    Yanjun Zhang
    Junqi Jia
    Yuan Fang
    Yin Tang
    Hongfei Wu
    Dong Fang
    Cell & Bioscience, 10
  • [32] Differential chromatin marking of introns and expressed exons by H3K36me3
    Paulina Kolasinska-Zwierz
    Thomas Down
    Isabel Latorre
    Tao Liu
    X Shirley Liu
    Julie Ahringer
    Nature Genetics, 2009, 41 : 376 - 381
  • [33] The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
    Li, Feng
    Mao, Guogen
    Tong, Dan
    Huang, Jian
    Gu, Liya
    Yang, Wei
    Li, Guo-Min
    CELL, 2013, 153 (03) : 590 - 600
  • [34] Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding
    Wang, Juncheng
    Qin, Su
    Li, Fudong
    Li, Sai
    Zhang, Wei
    Peng, Junhui
    Zhang, Zhiyong
    Gong, Qingguo
    Wu, Jihui
    Shi, Yunyu
    CELL RESEARCH, 2014, 24 (07) : 890 - 893
  • [35] The euchromatic histone mark H3K36me3 preserves heterochromatin through sequestration of an acetyltransferase complex in fission yeast
    Georgescu, Paula R.
    Capella, Matias
    Fischer-Burkart, Sabine
    Braun, Sigurd
    MICROBIAL CELL, 2020, 7 (03): : 80 - 92
  • [36] Histone Mutant Lifespan Screen Reveals That the H3k36me3 Promotes Longevity by Suppressing Intragenic Cryptic Transcription
    Dang, Weiwei
    Sen, Payel
    Dai, Junbiao
    Kaeberlein, Matt
    Kennedy, Brian
    Boeke, Jef D.
    Berger, Shelley
    GERONTOLOGIST, 2015, 55
  • [37] Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain
    van Nuland, Rick
    van Schaik, Frederik M. A.
    Simonis, Marieke
    van Heesch, Sebastiaan
    Cuppen, Edwin
    Boelens, Rolf
    Timmers, H. T. Marc
    van Ingen, Hugo
    EPIGENETICS & CHROMATIN, 2013, 6
  • [38] Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding
    Juncheng Wang
    Su Qin
    Fudong Li
    Sai Li
    Wei Zhang
    Junhui Peng
    Zhiyong Zhang
    Qingguo Gong
    Jihui Wu
    Yunyu Shi
    Cell Research, 2014, 24 : 890 - 893
  • [39] Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain
    Rick van Nuland
    Frederik MA van Schaik
    Marieke Simonis
    Sebastiaan van Heesch
    Edwin Cuppen
    Rolf Boelens
    HT Marc Timmers
    Hugo van Ingen
    Epigenetics & Chromatin, 6
  • [40] Distinct roles of H3K27me3 and H3K36me3 in vernalization response, maintenance, and resetting in winter wheat
    Liu, Xuemei
    Deng, Min
    Shi, Bingxin
    Zhu, Kehui
    Chen, Jinchao
    Xu, Shujuan
    Bie, Xiaomin
    Zhang, Xiansheng
    Lin, Xuelei
    Xiao, Jun
    SCIENCE CHINA-LIFE SCIENCES, 2024, 67 (10) : 2251 - 2266
12345