A facile regioselective synthesis of (5-amino-4-cyano-1H-imidazol-1-yl) benzoic acids

被引：1

作者：

Barros, Siria A. ^{[1
]}

Goncalves, M. Sameiro T. ^{[1
]}

Oliveira-Campos, Ana M. F. ^{[1
]}

Proenca, Fernanda R. P. ^{[1
]}

机构：

[1] Univ Minho, Ctr Chem, P-4710057 Braga, Portugal

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 44卷 / 01期

关键词：

D O I：

10.1002/jhet.5570440103

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient method was developped for the synthesis of 3-(5-amino-4-cyano-1H-imidazol-1-yl)-4-substituted benzoic acids 3. These compounds were isolated by intramolecular cyclisation of the corresponding 3-{[(Z)-2-amino-1,2-dicyano-vinyl]amino}methyleneaminobenzoic acids in the presence of base.

引用

页码：13 / 19

页数：7

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