Haem-oxygen reactive intermediates: catalysis by the two-step

被引：8

作者：

Makris, TM

Denisov, IG

Sligar, SG ^{[1
]}

机构：

[1] Univ Illinois, Dept Biochem, 505 S Goodwin Ave, Urbana, IL 61801 USA

[2] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

[3] Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA

[4] Univ Illinois, Coll Med, Urbana, IL 61801 USA

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2003年 / 31卷

关键词：

dioxygen activation; P450; mechanism;

D O I：

10.1042/BST0310516

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The catalytic schemes of a variety of haem enzymes, including the P450 mono-oxygenases, consist of a number of common reactive haem-oxygen adducts. The characterization of these intermediates by optical and EPR spectroscopies has reinforced the similarity of these intermediate states in a number of haem enzyme systems. Furthermore, the reactivity of these states in P450 and horseradish peroxidase, in which multiple potent oxidants are formed, provides a paradigm for many other haem enzymes.

引用

页码：516 / 519

页数：4

共 50 条

[1] Structures of the high-valent metal-ion haem-oxygen intermediates in peroxidases, oxygenases and catalases
Hersleth, Hans-Petter
Ryde, Ulf
Rydberg, Patrik
Gorbitz, Carl Henrik
Andersson, K. Kristoffer
JOURNAL OF INORGANIC BIOCHEMISTRY, 2006, 100 (04) : 460 - 476
[2] Two-step Two-intermediate Photorelease Bolm-McCulla Reaction: Dual Release of Nitrene and Atomic Oxygen Reactive Intermediates
Rashid, Mahir
Baker, Devora D.
Greer, Alexander
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2021, 97 (06) : 1453 - 1455
[3] The Role of Reactive Reaction Intermediates in Two-Step Heterogeneous Electrocatalytic Reactions: A Model Study
Fuhrmann, J.
Zhao, H.
Langmach, H.
Seidel, Y. E.
Jusys, Z.
Behm, R. J.
FUEL CELLS, 2011, 11 (04) : 501 - 510
[4] Two-step lipase catalysis for production of biodiesel
Talukder, Md. Mahabubur Rahman
Wu, Jin Chuan
Fen, Ng Mei
Melissa, Yeo Li Shi
BIOCHEMICAL ENGINEERING JOURNAL, 2010, 49 (02) : 207 - 212
[5] TWO-STEP MECHANISM IN HETEROGENEOUS CATALYSIS AND DYNAMIC ANALYSIS
陈诵英
彭少逸
杨争平
Journal of Chemical Industry and Engineering, 1992, (01) : 103 - 107
[6] Two-Step Amyloid Aggregation: Sequential Lag Phase Intermediates
Fabio Castello
Jose M. Paredes
Maria J. Ruedas-Rama
Miguel Martin
Mar Roldan
Salvador Casares
Angel Orte
Scientific Reports, 7
[7] Two-Step Amyloid Aggregation: Sequential Lag Phase Intermediates
Castello, Fabio
Paredes, Jose M.
Ruedas-Rama, Maria J.
Martin, Miguel
Roldan, Mar
Casares, Salvador
Orte, Angel
SCIENTIFIC REPORTS, 2017, 7
[8] Heme oxygen reactive intermediates: Catalysis across a rich functional landscape
Sligar, SG
Denisov, I
Makris, T
JOURNAL OF INORGANIC BIOCHEMISTRY, 2003, 96 (01) : 34 - 34
[9] REACTIVE INTERMEDIATES IN THIAMIN CATALYSIS
KLUGER, R
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1982, 378 (MAR) : 63 - 77
[10] Reactive intermediates in multicopper oxidase catalysis
Shin, Jieun
Winkler, Jay
Gray, Harry
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258

← 1 2 3 4 5 →