The hematopoietic system is mediated in part by cell-to-cell interactions and soluble mediators or growth factors (cytokines). A large number of cytokines directly and potently control hematopoietic stem and precursor cell proliferation and differentiation. This review focuses on the recent studies devoted to the role of cytokines in the ex vivo expansion and differentiation of hematopoietic stem and precursor cells.
机构:
George Washington Univ, Med Ctr, Dept Anat & Cell Biol, Washington, DC 20037 USAGeorge Washington Univ, Med Ctr, Dept Anat & Cell Biol, Washington, DC 20037 USA
Hawley, Robert G.
Ramezani, Ali
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机构:George Washington Univ, Med Ctr, Dept Anat & Cell Biol, Washington, DC 20037 USA
Ramezani, Ali
Hawley, Teresa S.
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机构:George Washington Univ, Med Ctr, Dept Anat & Cell Biol, Washington, DC 20037 USA
机构:
Alfred I duPont Hosp Children, Dept Pediat, Div Blood & Bone Marrow Transplantat, Wilmington, DE 19803 USAAlfred I duPont Hosp Children, Dept Pediat, Div Blood & Bone Marrow Transplantat, Wilmington, DE 19803 USA
机构:
Duke Univ, Med Ctr, Dept Med, Div Oncol & Transplantat, Durham, NC 27710 USADuke Univ, Med Ctr, Dept Med, Div Oncol & Transplantat, Durham, NC 27710 USA
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Louisiana State Univ, Hlth Sci Ctr, Gene Therapy Program, New Orleans, LA 70112 USALouisiana State Univ, Hlth Sci Ctr, Gene Therapy Program, New Orleans, LA 70112 USA
Schwarzenberger, P
Kolls, JK
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机构:Louisiana State Univ, Hlth Sci Ctr, Gene Therapy Program, New Orleans, LA 70112 USA
Kolls, JK
La Russa, V
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机构:Louisiana State Univ, Hlth Sci Ctr, Gene Therapy Program, New Orleans, LA 70112 USA