Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora

被引：1
|
作者：
Najafzadeh, M. J. [1 ,2 ,3 ]
Rezusta, A. [4 ]
Cameo, M. I. [4 ]
Zubiri, M. L. [5 ]
Yus, M. C.
Badali, H. [1 ,2 ]
Revillo, M. J. [4 ]
De Hoog, G. S. [1 ,2 ]
机构：
[1] Cent Bur Schimmelcultures, KNAW Fungal Biodivers Ctr, NL-3508 AD Utrecht, Netherlands
[2] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, NL-1012 WX Amsterdam, Netherlands
[3] Mashhad Univ Med Sci, Dept Parasitol & Mycol, Mashhad, Iran
[4] Microbiol Hosp Univ Miguel Servet, Inst Aragones Salud, Zaragoza, Spain
[5] Hosp Univ Miguel Servet, Zaragoza, Spain
来源：
MEDICAL MYCOLOGY | 2010年 / 48卷 / 02期
关键词：
Chromoblastomycosis; Fonsecaea monophora; itraconazole; DEEP MYCOSES; PEDROSOI; ITRACONAZOLE;
D O I：
10.3109/13693780903008813
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report a case of chromoblastomycosis in a 67-year-old female farmer, which involved a large (20 x 30 cm) cicatricial erythematous plaque on the inner side of her right thigh. The lesion was initially a small nodule which gradually extended over 36 years. Direct microscopic examination revealed a granulomatous lesion with muriform cells surrounded by giant cells. The mould recovered in cultures was dark olivaceous and identified as Fonsecaea monophora by ribosomal internal transcribe spacer (ITS) sequence data. The lesion was successfully cured after 4 months treatment with itraconazole, but there was a relapse.</.
引用
收藏
页码：390 / 393
页数：4
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