Combined factor V and VIII deficiency in Indian population

被引:0
|
作者
Shetty, S [1 ]
Madkaikar, M [1 ]
Nair, S [1 ]
Pawar, A [1 ]
Baindur, S [1 ]
Pathare, A [1 ]
Ghosh, K [1 ]
Mohanty, D [1 ]
机构
[1] Indian Council Med Res, Inst Immunohaematol, Parel 400012, Mumbai, India
关键词
factor V and VIII; inhibitors; mild;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The clinical and haematological heterogeneity in cases of the rare combined factor V and VIII deficiency has not been reported so far from India. Nine such cases belonging to five unrelated families have been analysed in the present study for the various haematological and clinical parameters. A very mild clinical presentation is seen in all these cases. The clinical manifestations, however, do not correlate with the plasma levels of these factors.
引用
收藏
页码:504 / 507
页数:4
相关论文
共 50 条
  • [31] Decreased Factor V Ameliorates Bleeding Diathesis in Patients with Combined Deficiency of Factor V and Factor VIII
    Shao, Yanyan
    Wu, Wenman
    Xu, Guanqun
    Wang Xuefeng
    Ding Qiulan
    BLOOD, 2018, 132
  • [32] Reduced bone density in individuals with combined factor V and VIII deficiency
    Mansouritorghabeh, H.
    Rezaieyazdi, Z.
    Rezai, J.
    HAEMOPHILIA, 2007, 13 (03) : 340 - 343
  • [33] Combined factor V and VIII deficiency: a new family and their haemorrhagic manifestations
    Mansouritorghabeh, H
    Rezaieyazdi, Z
    Pourfathollah, AA
    HAEMOPHILIA, 2006, 12 (02) : 169 - 171
  • [34] DECREASED FACTOR-VIII CLOTTING ANTIGEN LEVELS IN THE COMBINED FACTOR-V AND FACTOR-VIII DEFICIENCY
    SELIGSOHN, U
    ZIVELIN, A
    ZWANG, E
    THROMBOSIS RESEARCH, 1984, 33 (01) : 95 - 98
  • [35] NORMAL FACTOR-VIII ANTIGEN LEVEL IN COMBINED CONGENITAL DEFICIENCY FACTOR-V AND FACTOR-VIII
    GIROLAMI, A
    BAREGGI, G
    ACTA HAEMATOLOGICA, 1974, 51 (06) : 362 - 363
  • [36] Low factor V level ameliorates bleeding diathesis in patients with combined deficiency of factor V and factor VIII
    Shao, Yanyan
    Wu, Wenman
    Xu, Guanqun
    Wang, Xuefeng
    Ding, Qiulan
    BLOOD, 2019, 134 (20) : 1745 - 1754
  • [37] Genotype and phenotype report on patients with combined deficiency of factor V and factor VIII in Iran
    Karimi, M.
    Safarpour, M.
    Ekramzadeh, M.
    Afrasiabi, A.
    Haghpanah, S.
    Cairo, A.
    Peyvandi, F.
    HAEMOPHILIA, 2012, 18 : 185 - 186
  • [38] Bleeding symptoms in 27 Iranian patients with the combined deficiency of factor V and factor VIII
    Peyvandi, F
    Tuddenham, EGD
    Akhtari, AM
    Lak, M
    Mannucci, PM
    BRITISH JOURNAL OF HAEMATOLOGY, 1998, 100 (04) : 773 - 776
  • [39] Management of two patients with a combined Factor V and Factor VIII deficiency during pregnancy
    Menart, C
    Trzeciak, MC
    Attali, O
    Dechavanne, M
    Negrier, C
    THROMBOSIS AND HAEMOSTASIS, 1997, : P2983 - P2983
  • [40] Circumcision in a combined factor V and factor VIII deficiency using desmopressin (DDAVP) -: Reply
    Devecioglu, Ö
    TURKISH JOURNAL OF PEDIATRICS, 2003, 45 (01) : 86 - 86