A review of rodent models of peritoneal dialysis and its complications

被引:17
|
作者
Wang, Ji [1 ,2 ]
Liu, Shujun [1 ]
Li, Hongyu [3 ]
Sun, Jing [1 ]
Zhang, Sijin [2 ]
Xu, Xiaohong [1 ]
Liu, Yingying [1 ,4 ]
Wang, Yangwei [1 ]
Miao, Lining [1 ]
机构
[1] Jilin Univ, Hosp 2, Dept Nephrol, Changchun 130023, Peoples R China
[2] Jilin Univ, Hosp 2, Dept Pediat, Changchun 130023, Peoples R China
[3] Jilin Prov Canc Hosp, Dept Thorac Surg, Changchun, Peoples R China
[4] Jilin Univ, China Japan Union Hosp, Dept Nephrol, Changchun 130023, Peoples R China
关键词
Peritoneal dialysis; Rodent models; Peritoneal fibrosis; Peritoneal equilibration test; Peritonitis; GLUCOSE DEGRADATION-PRODUCTS; NITRIC-OXIDE SYNTHASE; LIPOPOLYSACCHARIDE-INDUCED PERITONITIS; SOLUTE TRANSPORT CHARACTERISTICS; LONG-TERM EXPOSURE; RAT MODEL; MOUSE MODEL; ANIMAL-MODEL; MORPHOLOGIC CHANGES; INFUSION MODEL;
D O I
10.1007/s11255-014-0829-4
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
This article reviews the available rodent models of peritoneal dialysis (PD) that have been developed over the past 20 years and the complications associated with their use. Although there are several methods used in different studies, the focus of this article is not to review or provide detailed summaries of these methods. Rather, this article reviews the most common methods of establishing a dialysis model in rodents, the assays used to observe function of the peritoneum in dialysis, and how these models are adapted to study peritonitis and peritoneal fibrosis. We compared the advantages and disadvantages of different methods, which should be helpful in studies of PD and may provide valuable data for further clinical studies.
引用
收藏
页码:209 / 215
页数:7
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