Applications of nuclear magnetic resonance spectroscopy (NMR) to combinatorial chemistry

被引：0
|
作者：
Yao, NH
He, WY
Liu, G [1 ]
机构：
[1] Peking Union, Coll Med, Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
[2] Univ Calif Davis, Davis Canc Ctr, Sacramento, CA 95817 USA
来源：
PROGRESS IN CHEMISTRY | 2004年 / 16卷 / 05期
关键词：
nuclear magnetic resonance spectroscopy; solid phase synthesis; solution-state NMR; high-throughput screening;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The analytical method that has the greatest impact on science is nuclear magnetic resonance spectroscopy. It is widely used in many fields. Combining author's research, the applications of nuclear magnetic resonance spectroscopy (NMR) to combinatorial chemistry, including applications of NMR to solid phase synthesis, analysis in solution and screening by NMR are reviewed.
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收藏
页码：696 / 707
页数：12
相关论文
共 75 条
  • [1] ANALYTICAL TECHNIQUES IN COMBINATORIAL CHEMISTRY - MAS CH CORRELATION IN SOLVENT-SWOLLEN RESIN
    ANDERSON, RC
    JAREMA, MA
    SHAPIRO, MJ
    STOKES, JP
    ZILIOX, M
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (09): : 2650 - 2651
  • [2] STRUCTURE DETERMINATION IN COMBINATORIAL CHEMISTRY - UTILIZATION OF MAGIC-ANGLE-SPINNING HMQC AND TOCSY NMR-SPECTRA IN THE STRUCTURE DETERMINATION OF WANG-BOUND LYSINE
    ANDERSON, RC
    STOKES, JP
    SHAPIRO, MJ
    [J]. TETRAHEDRON LETTERS, 1995, 36 (30) : 5311 - 5314
  • [3] ARAUJO DRL, 2001, QUIM NOVA, V24, P236
  • [4] Perspective articles on the utility and application of solution-phase combinatorial chemistry
    Baldino, CM
    [J]. JOURNAL OF COMBINATORIAL CHEMISTRY, 2000, 2 (02): : 89 - 103
  • [5] Multistep synthesis of 2,5-diketopiperazines on different solid supports monitored by high resolution magic angle spinning NMR spectroscopy
    Bianco, A
    Furrer, J
    Limal, D
    Guichard, G
    Elbayed, K
    Raya, J
    Piotto, M
    Briand, JP
    [J]. JOURNAL OF COMBINATORIAL CHEMISTRY, 2000, 2 (06): : 681 - 690
  • [6] Diffusion edited NMR: Screening compound mixtures by affinity NMR to detect binding ligands to vancomycin
    Bleicher, K
    Lin, MF
    Shapiro, MJ
    Wareing, JR
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (23): : 8486 - 8490
  • [7] SYNTHESIS, REACTIONS, AND C-13 FT NMR-SPECTROSCOPY OF POLYMER-BOUND STEROIDS
    BLOSSEY, EC
    CANNON, RG
    FORD, WT
    PERIYASAMY, M
    MOHANRAJ, S
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (15): : 4664 - 4668
  • [8] ENCODED COMBINATORIAL CHEMISTRY
    BRENNER, S
    LERNER, RA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) : 5381 - 5383
  • [9] A simple method for the generation of chloromethyl polystyrene on the Multipin™ solid support.
    Bui, CT
    Maeji, NJ
    Rasoul, F
    Bray, AM
    [J]. TETRAHEDRON LETTERS, 1999, 40 (29) : 5383 - 5386
  • [10] A GENERAL AND EXPEDIENT METHOD FOR THE SOLID-PHASE SYNTHESIS OF 1,4-BENZODIAZEPINE DERIVATIVES
    BUNIN, BA
    ELLMAN, JA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (27) : 10997 - 10998
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