Synthesis and biological evaluation of some 3H-quinazolin-4-one derivatives

被引：7
|
作者：
Sharaf, Afrah [1 ,2 ]
Ragab, Sherif Shaban [3 ]
Elbarbary, Ahmed A. [1 ,2 ]
Shaban, Elkhabiry [4 ]
El Sayed, Ibrahim El Tantawy [5 ]
机构：
[1] Tanta Univ, Dept Chem, Fac Sci, Tanta 31527, Egypt
[2] Jazan Univ, Fac Sci, Jazan 45142, Jizan, Saudi Arabia
[3] Natl Res Ctr NRC, Chem Ind Res Div, Photochem Dept, El Behouth St, Giza 12622, Egypt
[4] Natl Res Ctr, Dyeing Printing & Text Auxiliaries Dept, Text Res Div, El Behouth St, Giza 12622, Egypt
[5] Menoufia Univ, Dept Chem, Fac Sci, Shibin Al Kawm, Egypt
来源：
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2022年 / 19卷 / 01期
关键词：
Quinazolinones; Synthesis; Nucleosides; Biological; Antibacterial; HETEROCYCLIC-COMPOUNDS; AMINOPHOSPHONATES; THIOUREAS; MOIETY;
D O I：
10.1007/s13738-021-02315-8
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Starting from 3-phenylquinazoline-2,4(1H,3H)-dithione, some new derivatives of 3H-quinazoline-4-ones were synthesized. The structures of all new compounds were inferred based on the mass spectral, infrared, and NMR spectral data as well as the elemental analytical data. Some compounds were chosen for testing their biological activities as antibacterial, antifungal, and anticancer agents. [GRAPHICS] .
引用
收藏
页码：291 / 302
页数：12
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