Synthesis and biological evaluation of some 3H-quinazolin-4-one derivatives

被引：7

作者：

Sharaf, Afrah ^{[1
,2
]}

Ragab, Sherif Shaban ^{[3
]}

Elbarbary, Ahmed A. ^{[1
,2
]}

Shaban, Elkhabiry ^{[4
]}

El Sayed, Ibrahim El Tantawy ^{[5
]}

机构：

[1] Tanta Univ, Dept Chem, Fac Sci, Tanta 31527, Egypt

[2] Jazan Univ, Fac Sci, Jazan 45142, Jizan, Saudi Arabia

[3] Natl Res Ctr NRC, Chem Ind Res Div, Photochem Dept, El Behouth St, Giza 12622, Egypt

[4] Natl Res Ctr, Dyeing Printing & Text Auxiliaries Dept, Text Res Div, El Behouth St, Giza 12622, Egypt

[5] Menoufia Univ, Dept Chem, Fac Sci, Shibin Al Kawm, Egypt

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2022年 / 19卷 / 01期

关键词：

Quinazolinones; Synthesis; Nucleosides; Biological; Antibacterial; HETEROCYCLIC-COMPOUNDS; AMINOPHOSPHONATES; THIOUREAS; MOIETY;

D O I：

10.1007/s13738-021-02315-8

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Starting from 3-phenylquinazoline-2,4(1H,3H)-dithione, some new derivatives of 3H-quinazoline-4-ones were synthesized. The structures of all new compounds were inferred based on the mass spectral, infrared, and NMR spectral data as well as the elemental analytical data. Some compounds were chosen for testing their biological activities as antibacterial, antifungal, and anticancer agents. [GRAPHICS] .

引用

页码：291 / 302

页数：12

共 50 条

[1] Synthesis and biological evaluation of some 3H-quinazolin-4-one derivatives
Afrah Sharaf
Sherif Shaban Ragab
Ahmed A. Elbarbary
Elkhabiry Shaban
Ibrahim El Tantawy El Sayed
Journal of the Iranian Chemical Society, 2022, 19 : 291 - 302
[2] Synthesis, analgesic and anti-inflammatory evaluation of some new 3H-quinazolin-4-one derivatives
Alafeefy, Ahmed M.
Kadi, Adnan A.
El-Azab, Adel S.
Abdel-Hamide, Sami G.
Daba, Mohamad-Hesham Y.
ARCHIV DER PHARMAZIE, 2008, 341 (06) : 377 - 385
[3] Design, synthesis and anticonvulsant activity of some newer 3H-quinazolin-4-one derivatives
Amir, Mohd
Ali, Israr
Hassan, Mohd Zaheen
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2014, 53 (05): : 597 - 604
[4] Synthesis and biological activities of some new 3H-quinazolin-4-one derivatives derived from 3-phenylamino2-thioxo-3H-quinazolin-4-one
Saleh, MA
Hafez, YA
Abdel-Hay, FE
Gad, WI
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2004, 179 (02) : 411 - 426
[5] Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives
El-Sayed, Nahed N. E.
Almaneai, Norah M.
Ben Bacha, Abir
Al-Obeed, Omar
Ahmad, Rehan
Abdulla, Maha
Alafeefy, Ahmed M.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2019, 34 (01) : 672 - 683
[6] Design and Synthesis of New Derivatives of 3H-Quinazolin-4-One as Potential Anticonvulsant Agents
Kabra, Uma
Chopde, Chandrabhan
Wadodkar, Sudhir
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 48 (06) : 1351 - 1355
[7] Synthesis of New Quinazolin-4-(3H)-one Derivatives and Evaluation of Their Biological Activities
Mostafavi, Hamid
Islami, Mohammad Reza
Khabazzadeh, Hojatollah
Khaleghi, Moj
CHEMISTRYSELECT, 2019, 4 (11): : 3169 - 3174
[8] Investigation of Some 3H-Quinazolin-4-One Derivatives in Vitro Antimicrobial Effect and Cytotoxicity on Human Gingival Fibroblasts
Demirel, Ural Ufuk
Yilmaz, Aydan
Turkdagi, Hatice
Ozturk, Bahadir
Arslan, Ugur
POLYCYCLIC AROMATIC COMPOUNDS, 2021, 41 (08) : 1623 - 1630
[9] Synthesis and Anticancer Evaluation of Some Novel Quinazolin-4(3H)-one Derivatives
Gouhar, Rasha S.
Haneen, David S. A.
El-Hallouty, Salwa M.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2019, 56 (05) : 1651 - 1660
[10] Synthesis and antiproliferative evaluation of some novel quinazolin-4(3H)-one derivatives
Salem, Marwa Sayed
Al-Mabrook, Selima Ali Mohamed
El-Hashash, Maher Abd El-Aziz Mahmoud
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020, 57 (11) : 3898 - 3906

← 1 2 3 4 5 →