The calcium paradox - What should we have to fear?

被引：4
|
作者：
Barboza de Oliveira, Marcos Aurelio [1 ]
Brandi, Antonio Carlos [1 ]
dos Santos, Carlos Alberto [1 ]
Husseni Botelho, Paulo Henrique [1 ]
Lasso Cortez, Jose Luis [1 ]
Goissis, Gilberto [1 ]
Braile, Domingo Marcolino [1 ]
机构：
[1] Sao Jose do Rio Preto Med Sch FAMERP, Sao Jose Do Rio Preto, SP, Brazil
来源：
REVISTA BRASILEIRA DE CIRURGIA CARDIOVASCULAR | 2014年 / 29卷 / 02期
关键词：
Heart Arrest; induced; Myocardial Ischemia; Calcium; PERFUSED RAT-HEART; ENZYME-RELEASE; CARDIAC-MUSCLE; TEMPERATURE-DEPENDENCE; SARCOPLASMIC-RETICULUM; RABBIT MYOCARDIUM; ADULT-RAT; HYPOTHERMIA; CAFFEINE; ULTRASTRUCTURE;
D O I：
10.5935/1678-9741.20140054
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The calcium paradox was first mentioned in 1966 by Zimmerman et al. Thereafter gained great interest from the scientific community due to the fact of the absence of calcium ions in heart muscle cells produce damage similar to ischemia-reperfusion. Although not all known mechanisms involved in cellular injury in the calcium paradox intercellular connection maintained only by nexus seems to have a key role in cellular fragmentation. The addition of small concentrations of calcium, calcium channel blockers, and hyponatraemia hypothermia are important to prevent any cellular damage during reperfusion solutions with physiological concentration of calcium.
引用
收藏
页码：249 / 254
页数：6
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