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Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, MOE Key Lab Environm & Hlth,Inst Environm Med, Wuhan, Hubei, Peoples R China Hubei Univ Chinese Med, Sch Lab Med, 1 Huangjia Lake West Rd, Wuhan 430065, Hubei, Peoples R China