Long-Term Treatment of Atopic Dermatitis

被引：22
|
作者：
Prezzano, James C. [1 ]
Beck, Lisa A. [1 ]
机构：
[1] Univ Rochester, Med Ctr, Dept Dermatol, 601 Elmwood Ave, Rochester, NY 14642 USA
来源：
DERMATOLOGIC CLINICS | 2017年 / 35卷 / 03期
关键词：
Long-term; Atopic dermatitis; Eczema; Treatment; Topical therapy; Systemic therapy; PIMECROLIMUS CREAM 1-PERCENT; 0.1-PERCENT TACROLIMUS OINTMENT; DOUBLE-BLIND; FLUTICASONE PROPIONATE; MAINTENANCE TREATMENT; ADULT PATIENTS; RHEUMATOID-ARTHRITIS; PEDIATRIC-PATIENTS; FLARE-PROGRESSION; CYCLOSPORINE-A;
D O I：
10.1016/j.det.2017.02.007
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Many patients with mild to moderate atopic dermatitis (AD) are managed by identifying and avoiding allergens and irritants, ensuring skin moisturization, and graded use of topical corticosteroids and/or calcineurin inhibitors. There is little consensus on the next step. Most systemic therapies are "off label" in the United States and include phototherapy, cyclosporine, mycophenolic acid precursors, azathioprine, and methotrexate. The decision to use these therapies should be based on efficacy and safety readouts from well designed, long-term trials. This article reviews the long-term randomized, controlled trials examining safety and/or efficacy of interventions recommended for patients with mild to severe AD.
引用
收藏
页码：335 / +
页数：16
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