Blood biomarkers for HIV infection with focus on neurologic complications-A review

被引：2
|
作者：
Hagberg, Lars [1 ,2 ]
Eden, Arvid [1 ,2 ]
Zetterberg, Henrik [2 ,3 ,4 ,5 ,6 ]
Price, Richard W. [7 ]
Gisslen, Magnus [1 ,2 ]
机构：
[1] Univ Gothenburg, Sahlgrenska Acad, Inst Biomed, Dept Infect Dis, Gothenburg, Sweden
[2] Sahlgrens Univ Hosp, Reg Vastra Gotaland, Gothenburg, Sweden
[3] Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Psychiat & Neurochem, Molndal, Sweden
[4] UCL Inst Neurol, Dept Neurodegenerat Dis, London, England
[5] UK Dementia Res Inst UCL, London, England
[6] Hong Kong Ctr Neurodegenerat Dis, Hong Kong, Peoples R China
[7] Univ Calif San Francisco, Dept Neurol, San Francisco, CA USA
来源：
ACTA NEUROLOGICA SCANDINAVICA | 2022年 / 146卷 / 01期
基金：
欧盟地平线“2020”; 欧洲研究理事会; 瑞典研究理事会;
关键词：
blood biomarkers; HIV; neurology; NEUROFILAMENT PROTEIN NFL; CENTRAL-NERVOUS-SYSTEM; IMMUNE ACTIVATION; NEUROCOGNITIVE IMPAIRMENT; NEURONAL INJURY; DISORDERS; MARKERS; WOMEN;
D O I：
10.1111/ane.13629
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA concentrations, CD4 +T-cell count, and neurofilament light chain protein (NfL) concentration, along with tests for opportunistic infections can provide important information for clinical decisions.
引用
收藏
页码：56 / 60
页数：5
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