Polarization-resolved second-harmonic-generation optical coherence tomography in collagen

被引:42
|
作者
Applegate, BE [1 ]
Yang, CH
Rollins, AM
Izatt, JA
机构
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
[2] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA
关键词
D O I
10.1364/OL.29.002252
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We describe a novel imaging technique, second-harmonic-generation optical coherence tomography (SHOCT). This technique combines the spatial resolution and depth penetration of optical coherence tomography (OCT) with the molecular sensitivity of second-harmonic-generation spectroscopy. As a consequence of the coherent detection required for OCT, polarization,resolved images arise naturally. We demonstrate this new technique on a skin sample from the belly of Icelandic salmon, acquiring polarization-resolved SHOCT and OCT images simultaneously. (C) 2004 Optical Society of America.
引用
收藏
页码:2252 / 2254
页数:3
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