High percentage of resistance to ciprofloxacin and qnrB19 gene identified in urinary isolates of extended-spectrum β-lactamase-producing Escherichia coli in Madrid, Spain

被引:6
|
作者
Rios, Esther [1 ]
Rodriguez-Avial, Iciar [1 ]
Rodriguez-Avial, Carmen [1 ]
Hernandez, Elena [1 ]
Jose Picazo, Juan [1 ]
机构
[1] Hosp Clin San Carlos, Microbiol Serv, Madrid 28040, Spain
关键词
qnr; E; coli; Fluoroquinolone; Resistance; MEDIATED QUINOLONE RESISTANCE; KLEBSIELLA-PNEUMONIAE; FLUOROQUINOLONE RESISTANCE; MOLECULAR EPIDEMIOLOGY; PLASMID; ENTEROBACTERIACEAE; PREVALENCE; EMERGENCE; DETERMINANTS;
D O I
10.1016/j.diagmicrobio.2010.03.007
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The presence of qnr genes in 191 extended-spectrum beta-lactamase producing Escherichia coli from 2005, with 75% of resistance to ciprofloxacin, was evaluated. An SHV-12-producing E. coli carried qnrB19; both genes were transferred by conjugation. No gnrA- or gnrS-positive strains were detected. In addition, we identified 3 new parC mutations (S80W, E84R, and E84A). (C) 2010 Elsevier Inc. All rights reserved.
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页码:380 / 383
页数:4
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