Synthesis and anti-tumor activity of marine alkaloids

被引：9
|
作者：
Zhou, Shiyang [1 ,2 ]
Huang, Gangliang [1 ]
Chen, Guangying [2 ]
机构：
[1] Chongqing Normal Univ, Coll Chem, Chongqing 401331, Peoples R China
[2] Hainan Normal Univ, Coll Chem & Chem Engn, Key Lab Trop Med Resource Chem, Key Lab Trop Med Plant Chem Hainan Prov,Minist Ed, Haikou 571158, Hainan, Peoples R China
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2021年 / 41卷
关键词：
Marine alkaloid; Synthesis; Anti-tumor activity; ARYLOXYETHYL THIOCYANATE DERIVATIVES; NATURAL-PRODUCTS; DNA-DAMAGE; BIOLOGICAL EVALUATION; ANTICANCER ACTIVITY; COMET ASSAY; IN-VITRO; INDOLE ALKALOIDS; ANTIPROLIFERATIVE ACTIVITY; CYTOTOXICITY EVALUATION;
D O I：
10.1016/j.bmcl.2021.128009
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Marine alkaloids were divided into five categories from the perspective of anti-tumor activity. The optimization process, chemical synthesis, anti-tumor activity evaluation and structure?activity relationship of various com-pounds were discussed.
引用
收藏
页数：15
相关论文
共 50 条
  • [21] Synthesis and anti-tumor activity of alkenyl camptothecin esters
    Cao, ZS
    Mendoza, J
    Dejesus, A
    Giovanella, B
    [J]. ACTA PHARMACOLOGICA SINICA, 2005, 26 (02) : 235 - 241
  • [22] Synthesis and Anti-Tumor Activity of New Isatin Derivatives
    Jialing Wang
    Linlin Fu
    Chang Wang
    Xuelian Zhang
    Zhuo Wang
    Xuemei Zhao
    [J]. Russian Journal of General Chemistry, 2023, 93 : 1468 - 1473
  • [23] Synthesis and Anti-Tumor Activity of New Isatin Derivatives
    Wang, Jialing
    Fu, Linlin
    Wang, Chang
    Zhang, Xuelian
    Wang, Zhuo
    Zhao, Xuemei
    [J]. RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2023, 93 (06) : 1468 - 1473
  • [24] SYNTHESIS AND ANTI-TUMOR ACTIVITY OF TENUAZONIC ACID ANALOGUES
    YUKI, H
    KARIYA, K
    HASHIMOTO, Y
    [J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 1967, 15 (05) : 727 - +
  • [25] Synthesis and Anti-tumor Activity of Novel Garcinol Analogs
    Zhou, Huiyuan
    Wu, Yanlin
    Huang, Dianhong
    Zhang, Mingting
    Chen, Huanming
    Qian, Mingcheng
    Zhao, Shuai
    Zhang, Xinyan
    Chen, Xin
    [J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 40 (06) : 1578 - 1587
  • [26] Synthesis and anti-tumor activity of alkenyl camptothecin esters
    Zhi-song Cao
    John Mendoza
    Albert Dejesus
    Beppino Giovanella
    [J]. Acta Pharmacologica Sinica, 2005, 26 : 235 - 241
  • [27] Synthesis and anti-tumor activity of Fissitungfine B compounds
    Zhou, Shiyang
    Zhou, Xiaofeng
    Huang, Gangliang
    [J]. CHEMICAL BIOLOGY & DRUG DESIGN, 2022, 100 (03) : 305 - 312
  • [28] Synthesis and anti-tumor activity of glycosyl oxadiazoles derivatives
    Du, Kui
    Cao, Xianting
    Zhang, Pengfei
    Zheng, Hui
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (22) : 5318 - 5320
  • [29] SYNTHESIS AND ANTI-TUMOR ACTIVITY OF NEW PLATINUM COMPLEXES
    BROWN, DB
    KHOKHAR, AR
    HACKER, MP
    LOKYS, L
    BURCHENAL, JH
    NEWMAN, RA
    MCCORMACK, JJ
    FROST, D
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (08) : 952 - 956
  • [30] Synthesis and SAR studies of phenanthroindolizidine and phenanthroquinolizidine alkaloids as potent anti-tumor agents
    Wang, Ziwen
    Wu, Meng
    Wang, Yi
    Li, Zheng
    Wang, Lei
    Han, Guifang
    Chen, Fazhong
    Liu, Yuxiu
    Wang, Kailiang
    Zhang, Ao
    Meng, Linghua
    Wang, Qingmin
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 51 : 250 - 258
12345