Synthesis and anti-tumor activity of marine alkaloids

被引：9
|
作者：
Zhou, Shiyang [1 ,2 ]
Huang, Gangliang [1 ]
Chen, Guangying [2 ]
机构：
[1] Chongqing Normal Univ, Coll Chem, Chongqing 401331, Peoples R China
[2] Hainan Normal Univ, Coll Chem & Chem Engn, Key Lab Trop Med Resource Chem, Key Lab Trop Med Plant Chem Hainan Prov,Minist Ed, Haikou 571158, Hainan, Peoples R China
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2021年 / 41卷
关键词：
Marine alkaloid; Synthesis; Anti-tumor activity; ARYLOXYETHYL THIOCYANATE DERIVATIVES; NATURAL-PRODUCTS; DNA-DAMAGE; BIOLOGICAL EVALUATION; ANTICANCER ACTIVITY; COMET ASSAY; IN-VITRO; INDOLE ALKALOIDS; ANTIPROLIFERATIVE ACTIVITY; CYTOTOXICITY EVALUATION;
D O I：
10.1016/j.bmcl.2021.128009
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Marine alkaloids were divided into five categories from the perspective of anti-tumor activity. The optimization process, chemical synthesis, anti-tumor activity evaluation and structure?activity relationship of various com-pounds were discussed.
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页数：15
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