As time goes by

被引：6
|
作者：
Danovi, Safia [1 ]
机构：
[1] Canc Res UK, London, England
来源：
NATURE REVIEWS CANCER | 2016年 / 16卷 / 06期
关键词：
D O I：
10.1038/nrc.2016.53
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Kauret al. show that in older patients, fibroblasts in the melanoma microenvironment produce the WNT–β-catenin inhibitor secreted frizzled-related protein 2 (SFRP2), which increases oxidative stress in melanoma cells, driving metastasis and therapeutic resistance.
引用
收藏
页码：342 / 342
页数：1
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