As time goes by

被引：6

作者：

Danovi, Safia ^{[1
]}

机构：

[1] Canc Res UK, London, England

来源：

NATURE REVIEWS CANCER | 2016年 / 16卷 / 06期

关键词：

D O I：

10.1038/nrc.2016.53

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Kauret al. show that in older patients, fibroblasts in the melanoma microenvironment produce the WNT–β-catenin inhibitor secreted frizzled-related protein 2 (SFRP2), which increases oxidative stress in melanoma cells, driving metastasis and therapeutic resistance.

引用

页码：342 / 342

页数：1

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