Is canalization more than just a beautiful idea?

被引:9
|
作者
Sato, Kaoru [1 ]
Siomi, Haruhiko [1 ]
机构
[1] Keio Univ, Sch Med, Dept Mol Biol, Shinjuku Ku, Tokyo 1608582, Japan
来源
GENOME BIOLOGY | 2010年 / 11卷 / 03期
关键词
ELEMENTS; HSP90;
D O I
10.1186/gb-2010-11-3-109
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.
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页数:4
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