共 50 条
Is canalization more than just a beautiful idea?
被引:9
|作者:
Sato, Kaoru
[1
]
Siomi, Haruhiko
[1
]
机构:
[1] Keio Univ, Sch Med, Dept Mol Biol, Shinjuku Ku, Tokyo 1608582, Japan
来源:
关键词:
ELEMENTS;
HSP90;
D O I:
10.1186/gb-2010-11-3-109
中图分类号:
Q81 [生物工程学(生物技术)];
Q93 [微生物学];
学科分类号:
071005 ;
0836 ;
090102 ;
100705 ;
摘要:
The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.
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