Towards novel anti-cancer agents: Tetrahydroquinoline-based small-molecules as selective Mcl-1 inhibitors

被引：0
|
作者：
Chen, Lijia [1 ]
Yap, Jeremy L. [1 ]
Gallagher, Catherine [2 ,3 ]
Walensky, Loren D. [2 ,3 ]
Fletcher, Steven [1 ]
机构：
[1] Univ Maryland, Sch Pharm, Dept Pharmaceut Sci, Baltimore, MD 21201 USA
[2] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Pediat Oncol, Boston, MA 02215 USA
[3] Harvard Univ, Sch Med, Childrens Hosp Boston, Boston, MA 02215 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 247卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
326-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
    Jiahuai Tan
    Shundong Cang
    Yuehua Ma
    Richard L Petrillo
    Delong Liu
    Journal of Hematology & Oncology, 3
  • [32] Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
    Tan, Jiahuai
    Cang, Shundong
    Ma, Yuehua
    Petrillo, Richard L.
    Liu, Delong
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2010, 3
  • [33] Recent Advances in the Development of Selective Mcl-1 Inhibitors for the Treatment of Cancer (2017-Present )
    Fan, Ying
    Hou, Xuben
    Fang, Hao
    RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY, 2020, 15 (04) : 306 - 320
  • [34] N-glycosylation inhibitors towards novel anti-cancer chemotherapeutics
    Mitachi, Katsuhiko
    Eslamimehr, Shakiba
    Kurosu, Sara
    Kurosu, Michio
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [35] Synthesis and biological evaluation of novel oxindole-based RTK inhibitors as anti-cancer agents
    Chen, Gaozhi
    Weng, Qiaoyou
    Fu, Lili
    Wang, Zhe
    Yu, Pengtian
    Liu, Zhiguo
    Li, Xiaokun
    Zhang, Huajie
    Liang, Guang
    BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 22 (24) : 6953 - 6960
  • [36] Induction of nucleosome disassembly with small molecules as a novel anti-cancer approach
    Safina, Alfiya
    Sandlesh, Poorva
    Wang, Jianmin
    Gurova, Katerina, V
    CANCER RESEARCH, 2020, 80 (16)
  • [37] Small molecule KDM4s inhibitors as anti-cancer agents
    Lin, Hongzhi
    Li, Qihang
    Li, Qi
    Zhu, Jie
    Gu, Kai
    Jiang, Xueyang
    Hu, Qianqian
    Feng, Feng
    Qu, Wei
    Chen, Yao
    Sun, Haopeng
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2018, 33 (01) : 777 - 793
  • [38] The Application of Small Molecule ClpP Agonists as Novel Anti-Cancer Agents
    Graves, L.
    Daglish, S.
    Canterbury, O.
    Mistreanu, A.
    Graves, P.
    Iwanowicz, E.
    EUROPEAN JOURNAL OF CANCER, 2024, 211 : S22 - S22
  • [39] Small molecule Mcl-1 inhibitors induce apoptosis and death in multiple cancer subtypes in vitro
    Sensintaffar, John L.
    Arnold, Allison
    Goodwin, Craig
    Hogdal, Leah
    Shaw, Subrata
    Tarr, James C.
    Lee, Taekyu
    Olejniczak, Edward
    Fesik, Stephen W.
    CANCER RESEARCH, 2016, 76
  • [40] Characterization of small molecule inhibitors of ubiquitin specific peptidase 1 (USP1) as anti-cancer agents
    Brenndorfer, E.
    Jonsson, D.
    Bohm, K.
    Eneroth, A.
    Acs, K.
    Henderson, I.
    Kullman-Magnusson, M.
    Rydergard, C.
    Stenberg, G.
    Sternbeck, A. K.
    Ulander, E.
    Albertella, M.
    Bethell, R.
    EUROPEAN JOURNAL OF CANCER, 2018, 103 : E31 - E32
12345