Antitumour activity of Bauhinia variegata against Ehrlich ascites carcinoma induced mice

被引：8
|
作者：
Rajkapoor, B
Jayakar, B
Murugesh, N
机构：
[1] Vinayaka Miss Coll Pharm, Dept Pharmacol, Salem 636008, Tamil Nadu, India
[2] Madurai Med Coll, Inst Pharmacol, Madurai 625020, Tamil Nadu, India
来源：
PHARMACEUTICAL BIOLOGY | 2003年 / 41卷 / 08期
关键词：
Bauhinia variegata; Ehrlich ascites carcinoma; heamotological sutides; in vitro cytotoxicity; life span; solid tumour;
D O I：
10.1080/13880200390501947
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The antitumour activity of ethanol extract of Bauhinia variegata (EBV) has been evaluated against Ehrlich ascites carcinoma (EAC) in Swiss albino mice. A significant enhancement of mean survival time of EBV treated tumour bearing mice was found with respect to the control group. EBV treatment was found to enhance peritoneal cell counts. After,14 days of inoculation, EBV is able to reverse the changes in the haemotological parameters, protein and PCV consequent to tumour inoculation. Oral administration of EBV was effective in reducing solid tumour mass development induced by EAC cells. EBV was found to be a potent cytotoxic. towards EAC tumour cells.
引用
收藏
页码：604 / 607
页数：4
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