Phenotype of acute respiratory syncytial virus induced lower respiratory tract illness in infancy and subsequent morbidity

被引：14
|
作者：
Elphick, H. E.
Ritson, S.
Rigby, A. S.
Everard, M. L. [1 ]
机构：
[1] Sheffield Childrens Hosp, Western Bank, Sheffield S10 2TH, S Yorkshire, England
[2] Sheffield Childrens Hosp, Div Child Hlth, Sheffield S10 2TH, S Yorkshire, England
[3] Univ Hull, Acad Dept Cardiol, Kingston Upon Hull, Yorks, England
来源：
ACTA PAEDIATRICA | 2007年 / 96卷 / 02期
关键词：
atopy; infant; morbidity; phenotype; RSV; wheeze;
D O I：
10.1111/j.1651-2227.2007.00082.x
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The objective of this study was to investigate the association hypothesis that outcome following respiratory syncytial virus (RSV) induced bronchiolitis (RSVB) and RSV induced wheeze (RSVW) are different. At 3 years respiratory symptoms were more common in those with RSV infection than the control group but there was no increase in allergic sensitisation (11% vs 10%). Those with RSVW were more likely to have evidence of allergic sensitisation when compared with RSVB subjects (22% vs 7%), and have increased symptoms and increased use of inhaled steroids. Conclusion: The data argue that RSV infection during infancy does not induce allergic asthma and that host factors rather than the virus determine long-term outcomes.
引用
收藏
页码：307 / 309
页数：3
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