Nanoscale fiber tip probe for biomedical sensing

被引：0
|
作者：
Quan, Q. [1 ]
Liang, F. [1 ]
Hong, W. [2 ]
Schaak, D. [1 ]
Loncar, M. [3 ]
机构：
[1] Harvard Univ, Rowland Inst, 100 Edwin Land Blvd, Cambridge, MA 02142 USA
[2] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA
[3] Sch Engn & Appl Sci, Cambridge, MA 02138 USA
来源：
BIOSENSING AND NANOMEDICINE VII | 2014年 / 9166卷
关键词：
Single cells; surface plasmon resonance; optical fiber;
D O I：
10.1117/12.2062485
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Most traditional biological assays are based on ensemble measurements on cells. Due to lack of the detection sensitivity and efficiency in sample preparation, analyzing proteins in single cells have been challenging. Here we describe an assay-on-a-tip platform, and demonstrate an in situ, label-free technique to detect proteins inside single cells.
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页数：5
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