MEK inhibition enhances gemcitabine efficacy by increasing MDM2-mediated ubiquitination and degradation of RRM1

被引：0
|
作者：
Vena, F. [1 ]
Li Causi, E. [2 ]
Hagemann, T. [2 ]
Hartley, J. A. [1 ]
Goodstal, S. [3 ]
Hochhauser, D. [1 ]
机构：
[1] UCL, UCL Canc Inst, London, England
[2] Barts Canc Inst, London, England
[3] EMD Serono, Res Inst, Billerica, MA USA
来源：
EUROPEAN JOURNAL OF CANCER | 2014年 / 50卷
关键词：
D O I：
10.1016/S0959-8049(14)70571-4
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
445
引用
收藏
页码：146 / 146
页数：1
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