Sesquiterpene lactones from Anthemis melanolepis

被引：9
|
作者：
Saroglou, Vasiliki
Karioti, Anastasia
Heilmann, Joerg
Kypriotakis, Zacharias
Skaltsa, Helen [1 ]
机构：
[1] Univ Athens, Sch Pharm, Dept Pharmacognosy & Chem Nat Prod, GR-15771 Athens, Greece
[2] Univ Regensburg, Dept Pharmaceut Biol, Inst Pharm, D-93053 Regensburg, Germany
[3] Inst Educ Technol, Sch Agr Prod, Lab Taxonomy & Management Wild Flora, Heraclion Crete 71110, Greece
来源：
HELVETICA CHIMICA ACTA | 2007年 / 90卷 / 01期
关键词：
D O I：
10.1002/hlca.200790012
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
From the aerial parts of A. melanolepis, two new sesquiterpene lactones, melanolepin B (= 1 alpha,4 beta,8 alpha-atrihydroxyeudesm-11(13)-en-12,6 alpha-olide; 1) and melanolepin C (= 1 alpha,10 beta-epoxy-8 beta-hydroxygermacra-4(15),11(13)-dien-12,6 alpha-olide; 2), were isolated, together with four known compounds, desacetyllaurenobiolide, dentatin A, taraxasterol, and (3S,5R)-loliolide. Compound 1 was found to have the rare cis-fused eudesmane skeleton. The structures of the isolated compounds were established by means of NMR (H-1, H-1-COSY,H-1,C-13-HSQC, HMBC, NOESY) and MS analyses.
引用
收藏
页码：171 / 175
页数：5
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