Discovery of FAK Inhibitors Using Structure Based Drug Design

被引：1
|
作者：
Nam, Ky-Youb [1 ]
Jin, Dong-Hoon [2 ]
No, Kyoung Tai [3 ]
Ahn, Soon Kil [4 ]
机构：
[1] Asan Med Ctr, Ctr Dev & Commercializat Anticanc Therapeut, Seoul 138736, South Korea
[2] Univ Ulsan Coll Med, Asan Med Ctr, Dept Convergence Med, Asan Inst Life Sci, Seoul 138736, South Korea
[3] Yonsei Univ, Dept Biotechnol, Seoul 120749, South Korea
[4] Incheon Natl Univ, Div Life Sci, Inst New Drug Dev, Inchon 406772, South Korea
来源：
BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2014年 / 35卷 / 11期
关键词：
Focal adhesion kinase 1; Kinase inhibitor; Anticancer drug; Quantum mechanical calculations; Structure-based drug design; FOCAL ADHESION KINASE; HUMAN BREAST; PREDICTION; TISSUES;
D O I：
10.5012/bkcs.2014.35.11.3156
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
[No abstract available]
引用
收藏
页码：3156 / 3157
页数：2
相关论文
共 50 条
  • [41] Natural Products as Enzyme Inhibitors in Drug Design and Discovery
    Orhan, Ilkay Erdogan
    [J]. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2022, 22 (03) : 188 - 188
  • [42] Fragment-based drug discovery using rational design
    Jhoti, H.
    [J]. SPARKING SIGNALS: KINASES AS MOLECULAR SIGNAL TRANSDUCERS AND PHARMACOLOGICAL DRUG TARGETS IN INFLAMMATION, 2008, 3 : 169 - 185
  • [43] THE INTEGRATION OF STRUCTURE-BASED DRUG DESIGN & COMBINATORIAL CHEMISTRY FOR EFFICIENT DRUG DISCOVERY
    Salemme, F. Raymond
    [J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 1996, 52 : C4 - C4
  • [44] Structure-Based Drug Design: A Key Technology for Drug Discovery in the Pharmaceutical Industry
    Ohta, Masateru
    [J]. JOURNAL OF CARDIAC FAILURE, 2015, 21 (10) : S160 - S160
  • [45] Design and synthesis of indolylpyridone derivatives for use as CHK1 inhibitors: A case study in structure based drug discovery
    Fiumana, Andrea
    Bedford, Simon
    Borgognoni, Jenifer
    Drysdale, Martin
    Foloppe, Nicolas
    Jordan, Allan M.
    Massey, Andrew
    Stokes, Stephen
    Web, Paul
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
  • [46] Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design
    Butler, Christopher R.
    Brodney, Michael A.
    Beck, Elizabeth M.
    Barreiro, Gabriela
    Nolan, Charles E.
    Pan, Feng
    Vajdos, Felix
    Parris, Kevin
    Varghese, Alison H.
    Helal, Christopher J.
    Lira, Ricardo
    Doran, Shawn D.
    Riddell, David R.
    Buzon, Leanne M.
    Dutra, Jason K.
    Martinez-Alsina, Luis A.
    Ogilvie, Kevin
    Murray, John C.
    Young, Joseph M.
    Atchison, Kevin
    Robshaw, Ashley
    Gonzales, Cathleen
    Wang, Jinlong
    Zhang, Yong
    O'Neill, Brian T.
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (06) : 2678 - 2702
  • [47] Structure-based drug design remains a key method for drug discovery and optimization
    Glaser, V
    [J]. GENETIC ENGINEERING NEWS, 1996, 16 (12): : 1 - &
  • [48] Discovery of Novel DNA Gyrase Inhibitors Against Salmonella Typhi using Structure Based Drug Delivery Approach
    Kapil, Arti
    Sharma, Priyanka
    Kaur, Punit
    Kumar, Manoj
    Dahiya, Sushila
    Sood, Seema
    Das, Bimal
    [J]. BIOPHYSICAL JOURNAL, 2020, 118 (03) : 72A - 73A
  • [49] Hit diffusion: limitations to drug discovery and structure-based design
    John H. Van Drie
    [J]. Journal of Computer-Aided Molecular Design, 2022, 36 : 373 - 379
  • [50] Hit diffusion: limitations to drug discovery and structure-based design
    Van Drie, John H.
    [J]. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2022, 36 (05) : 373 - 379
12345