Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Recipients (rc) and Suppress Recipient T-Cell (T) Response Against Donor Antigen

被引:0
|
作者
Okano, S. [1 ]
Kish, D. [2 ]
Keslar, K. [2 ]
Baldwin, W. [2 ]
Fairchild, R. [1 ]
Miller, C. [1 ]
Abu-Elmagd, K. [1 ]
Khanna, A. [1 ]
Fujiki, M. [1 ]
Fung, J. [1 ]
Costa, G. [1 ]
Hashimoto, K. [1 ]
机构
[1] Cleveland Clin, Dept Gen Surg, Digest Dis & Surg Inst, Transplant Ctr, Cleveland, OH 44106 USA
[2] Cleveland Clin, Lerner Res Inst, Dept Immunol, Cleveland, OH 44106 USA
关键词
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
460
引用
收藏
页码:368 / 368
页数:1
相关论文
共 50 条
  • [41] Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms
    Negorev, Dmitri
    Beier, Ulf H.
    Zhang, Tianyi
    Quatromoni, Jon G.
    Bhojnagarwala, Pratik
    Albelda, Steven M.
    Singhal, Sunil
    Eruslanov, Evgeniy
    Lohoff, Falk W.
    Levine, Matthew H.
    Diamond, Joshua M.
    Christie, Jason D.
    Hancock, Wayne W.
    Akimova, Tatiana
    SCIENTIFIC REPORTS, 2018, 8
  • [42] T-cell defect in diffuse large B-cell lymphomas involves expansion of myeloid-derived suppressor cells
    Azzaoui, Imane
    Uhel, Fabrice
    Rossille, Delphine
    Pangault, Celine
    Dulong, Joelle
    Le Priol, Jerome
    Lamy, Thierry
    Houot, Roch
    Le Gouill, Steven
    Cartron, Guillaume
    Godmer, Pascal
    Bouabdallah, Krimo
    Milpied, Noel
    Damaj, Gandhi
    Tarte, Karin
    Fest, Thierry
    Roussel, Mikael
    BLOOD, 2016, 128 (08) : 1081 - 1092
  • [43] Investigating immunosuppressive regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSC) in checkpoint inhibitor therapy of malignant melanoma
    Krebs, F.
    Mitzel-Rink, H.
    Jetter, A.
    Behling, J.
    Wickert, D.
    Lang, B.
    Hahn, S. A.
    Meissner, M.
    Tenzer, S.
    Grabbe, S.
    Loquai, C.
    Tuettenberg, A.
    EXPERIMENTAL DERMATOLOGY, 2017, 26 (03) : E67 - E67
  • [44] The Interactions of T Cells with Myeloid-Derived Suppressor Cells in Peripheral Blood Stem Cell Grafts
    Guan, Qingdong
    Gilpin, Scott G.
    Doerksen, James
    Bath, Lauren
    Lam, Tracy
    Li, Yun
    Lambert, Pascal
    Wall, Donna A.
    CELLS, 2024, 13 (18)
  • [45] L-Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells
    Fletcher, Matthew
    Ramirez, Maria E.
    Sierra, Rosa A.
    Raber, Patrick
    Thevenot, Paul
    Al-Khami, Amir A.
    Sanchez-Pino, Dulfary
    Hernandez, Claudia
    Wyczechowska, Dorota D.
    Ochoa, Augusto C.
    Rodriguez, Paulo C.
    CANCER RESEARCH, 2015, 75 (02) : 275 - 283
  • [46] AMV564, a novel bivalent, bispecific T-cell engager, targets myeloid-derived suppressor cells
    Eckard, Sterling
    Gehrs, Leah
    Smith, Victoria
    Guenot, Jeanmarie
    DiPersio, John
    Wei, Sheng
    Rettig, Michael
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [47] Modulation of CD8+ T-cell activation events by monocytic and granulocytic myeloid-derived suppressor cells
    Schouppe, Elio
    Van Overmeire, Eva
    Laoui, Damya
    Keirsse, Jiri
    Van Ginderachter, Jo A.
    IMMUNOBIOLOGY, 2013, 218 (11) : 1385 - 1391
  • [48] Notch-Signaling Deregulation Induces Myeloid-Derived Suppressor Cells in T-Cell Acute Lymphoblastic Leukemia
    Grazioli, Paola
    Orlando, Andrea
    Giordano, Nike
    Noce, Claudia
    Peruzzi, Giovanna
    Abdollahzadeh, Behnaz
    Screpanti, Isabella
    Campese, Antonio Francesco
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [49] Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T-Cell Transfer in Breast Cancer
    Alizadeh, Darya
    Trad, Malika
    Hanke, Neale T.
    Larmonier, Claire B.
    Janikashvili, Nona
    Bonnotte, Bernard
    Katsanis, Emmanuel
    Larmonier, Nicolas
    CANCER RESEARCH, 2014, 74 (01) : 104 - 118
  • [50] Arsenic trioxide inhibits tumor-induced myeloid-derived suppressor cells and enhances T-cell activity
    Gao, Qingmin
    Jiang, Jingwei
    Chu, Zhaohui
    Lin, Hao
    Zhou, Xinli
    Liang, Xiaohua
    ONCOLOGY LETTERS, 2017, 13 (04) : 2141 - 2150