Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Recipients (rc) and Suppress Recipient T-Cell (T) Response Against Donor Antigen

被引:0
|
作者
Okano, S. [1 ]
Kish, D. [2 ]
Keslar, K. [2 ]
Baldwin, W. [2 ]
Fairchild, R. [1 ]
Miller, C. [1 ]
Abu-Elmagd, K. [1 ]
Khanna, A. [1 ]
Fujiki, M. [1 ]
Fung, J. [1 ]
Costa, G. [1 ]
Hashimoto, K. [1 ]
机构
[1] Cleveland Clin, Dept Gen Surg, Digest Dis & Surg Inst, Transplant Ctr, Cleveland, OH 44106 USA
[2] Cleveland Clin, Lerner Res Inst, Dept Immunol, Cleveland, OH 44106 USA
关键词
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
460
引用
收藏
页码:368 / 368
页数:1
相关论文
共 50 条
  • [1] Myeloid-Derived Suppressor Cells Accumulate in Intestinal Transplant Patients and Suppress Anti-Donor T-Cell Responses to Donor Epithelial Stem Cells
    Okano, Shinji
    Abu-Elmagd, Kareem
    Fairchild, Robert L.
    Fujiki, Masato
    Khanna, Ajai
    Osman, Mohammed
    Costa, Guilherme
    Miller, Charles
    Hashimoto, Koji
    TRANSPLANTATION, 2017, 101 (06) : S95 - S95
  • [2] Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Patients
    Okano, S.
    Hashimoto, K.
    Abu-Elmagd, K.
    Fung, J.
    Kish, D.
    Keslar, K.
    Min, B.
    Fairchild, R.
    Miller, C.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 : 498 - 498
  • [3] Myeloid-derived suppressor cells accumulate in kidney allograft tolerance and specifically suppress effector T cell expansion
    Dugast, Anne-Sophie
    Haudebourg, Thomas
    Coulon, Flora
    Heslan, Michele
    Haspot, Fabienne
    Poirier, Nicolas
    de Silly, Romain Vuillefroy
    Usal, Claire
    Smit, Helga
    Martinet, Bernard
    Thebault, Pamela
    Renaudin, Karine
    Vanhove, Bernard
    JOURNAL OF IMMUNOLOGY, 2008, 180 (12): : 7898 - 7906
  • [4] Granulocytic Myeloid-Derived Suppressor Cells (GR-MDSC) in Breast Milk (BM); GR-MDSC Accumulate in Human BM and Modulate T-Cell and Monocyte Function
    Koestlin, Natascha
    Schoetensack, Carolin
    Schwarz, Julian
    Spring, Baerbel
    Marme, Alexander
    Goelz, Rangmar
    Brodbeck, Gerhard
    Poets, Christian F.
    Gille, Christian
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [5] Myeloid-derived suppressor cells (MDSC) in psoriasis are an expanded population with diverse T cell-suppressor mechanisms
    Chung, J.
    Feigenbaum, L.
    Cruz, P.
    Chong, B.
    Ariizumi, K.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2016, 136 (05) : S41 - S41
  • [6] Myeloid-derived suppressor cells increase and inhibit donor-reactive T cell responses to graft intestinal epithelium in intestinal transplant patients
    Okano, Shinji
    Abu-Elmagd, Kareem
    Kish, Danielle D.
    Keslar, Karen
    Baldwin, William M., III
    Fairchild, Robert L.
    Fujiki, Masato
    Khanna, Ajai
    Osman, Mohammed
    Costa, Guilherme
    Fung, John
    Miller, Charles
    Kayashima, Hiroto
    Hashimoto, Koji
    AMERICAN JOURNAL OF TRANSPLANTATION, 2018, 18 (10) : 2544 - 2558
  • [7] Monocytic myeloid-derived suppressor cells regulate T-cell responses against vaccinia virus
    Fortin, Carl
    Yang, Yiping
    Huang, Xiaopei
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2017, 47 (06) : 1022 - 1031
  • [8] T Cell Inhibition by Myeloid-Derived Suppressor Cells (MDSC) Is Mediated by iNOS Via Induction of Treg Cells
    Qin, J.
    Arakawa, Y.
    Chou, H. -S.
    Wang, L.
    Stuehr, D.
    Ghosh, A.
    Fung, J. J.
    Qian, S.
    Lu, L.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2012, 12 : 445 - 445
  • [9] Modulation of T-cell function by myeloid-derived suppressor cells in hematological malignancies
    Bhardwaj, Vaishali
    Ansell, Stephen M. M.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2023, 11
  • [10] Granulocytic and monocytic populations of tumor-infiltrating myeloid-derived suppressor cells (MDSC) suppress T cell proliferation through independent mechanisms
    Raber, Patrick
    Wyczechowska, Dorota
    Rodriguez, Paulo
    JOURNAL OF IMMUNOLOGY, 2012, 188