Improvement of nisin production in pH feed-back controlled, fed-batch culture by Lactococcus lactis subsp. lactis

被引:9
|
作者
Lv, WH [1 ]
Cong, W [1 ]
Cai, ZL [1 ]
机构
[1] Chinese Acad Sci, Grad Sch, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
关键词
fed-batch culture; Lactococcus lactis subsp lactis; nisin; pH feed-back;
D O I
10.1007/s10529-004-3742-6
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nisin production by Lactococcus lactis subsp. lactis in fed-batch culture was doubled by using a pH feed-back controlled method. Sucrose concentration was controlled at 10 g l(-1) giving 5010 IU nisin ml(-1) compared to 2660 IU nisin ml(-1) in batch culture.
引用
收藏
页码:1713 / 1716
页数:4
相关论文
共 50 条
  • [41] Enhancement of extracellular glucose oxidase production in pH-stat feed-back controlled fed-batch culture of recombinant Saccharomyces cerevisiae
    Kapat, A
    Jung, JK
    Park, YH
    [J]. BIOTECHNOLOGY LETTERS, 1998, 20 (07) : 683 - 686
  • [42] Enhanced nisin production by increasing genes involved in nisin Z biosynthesis in Lactococcus lactis subsp lactis A164
    Cheigh, CI
    Park, H
    Choi, HJ
    Pyun, YR
    [J]. BIOTECHNOLOGY LETTERS, 2005, 27 (03) : 155 - 160
  • [43] Loss of IrpT Function in Lactococcus lactis subsp. lactis N8 Results in Increased Nisin Resistance
    Zhengzheng Xuanyuan
    Zhenzhou Wu
    Ruiqing Li
    Dezhou Jiang
    Junjie Su
    Haijin Xu
    Yanling Bai
    Xiuming Zhang
    Per Erik Joakim Saris
    Mingqiang Qiao
    [J]. Current Microbiology, 2010, 61 : 329 - 334
  • [44] INFLUENCE OF THE PHOSPHORUS AND NITROGEN-SOURCE ON NISIN PRODUCTION IN LACTOCOCCUS-LACTIS SUBSP LACTIS BATCH FERMENTATIONS USING A COMPLEX MEDIUM
    DEVUYST, L
    VANDAMME, EJ
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1993, 40 (01) : 17 - 22
  • [45] Nisin Production of Lactococcus lactis N8 with Hemin-Stimulated Cell Respiration in Fed-Batch Fermentation System
    Kordikanlioglu, Burcu
    Simsek, Omer
    Saris, Per E. J.
    [J]. BIOTECHNOLOGY PROGRESS, 2015, 31 (03) : 678 - 685
  • [46] Nisin-controlled extracellular production of apidaecin in Lactococcus lactis
    Zhou, Xu-xia
    Wang, Yan-bo
    Pan, Yuan-jiang
    Li, Wei-fen
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2008, 78 (06) : 947 - 953
  • [47] Nisin-controlled extracellular production of apidaecin in Lactococcus lactis
    Xu-xia Zhou
    Yan-bo Wang
    Yuan-jiang Pan
    Wei-fen Li
    [J]. Applied Microbiology and Biotechnology, 2008, 78 : 947 - 953
  • [48] Prickly pear cactus as a raw material for lactic acid production by Lactococcus lactis subsp. lactis
    Tamine, Milouda
    Nancib, Aicha
    Nancib, Nabil
    Boudrant, Joseph
    [J]. MALAYSIAN JOURNAL OF MICROBIOLOGY, 2018, 14 (01) : 16 - 24
  • [49] INFLUENCE OF PH ON GROWTH AND BACTERIOCIN PRODUCTION BY LACTOCOCCUS-LACTIS SUBSP LACTIS 140NWC DURING BATCH FERMENTATION
    PARENTE, E
    RICCIARDI, A
    ADDARIO, G
    [J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1994, 41 (04) : 388 - 394
  • [50] Derivation of efficient nisin producers by fusing protoplasts of two allied strains of Lactococcus lactis subsp. lactis with low nisin-synthesizing abilities
    Stoyanova, LG
    Egorov, NS
    [J]. MICROBIOLOGY, 1998, 67 (01) : 38 - 44