Improvement of nisin production in pH feed-back controlled, fed-batch culture by Lactococcus lactis subsp. lactis

被引:9
|
作者
Lv, WH [1 ]
Cong, W [1 ]
Cai, ZL [1 ]
机构
[1] Chinese Acad Sci, Grad Sch, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100080, Peoples R China
关键词
fed-batch culture; Lactococcus lactis subsp lactis; nisin; pH feed-back;
D O I
10.1007/s10529-004-3742-6
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nisin production by Lactococcus lactis subsp. lactis in fed-batch culture was doubled by using a pH feed-back controlled method. Sucrose concentration was controlled at 10 g l(-1) giving 5010 IU nisin ml(-1) compared to 2660 IU nisin ml(-1) in batch culture.
引用
收藏
页码:1713 / 1716
页数:4
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