Statistical Test/Estimation Methods Used in Contemporary Phase III Cancer Randomized Controlled Trials with Time-to-Event Outcomes

被引:8
|
作者
Uno, Hajime [1 ,2 ]
Horiguchi, Miki [1 ]
Hassett, Michael J. [1 ]
机构
[1] Dana Farber Canc Inst, Dept Med Oncol, 450 Brookline Ave, Boston, MA 02215 USA
[2] Dana Farber Canc Inst, Dept Data Sci, Boston, MA 02115 USA
来源
ONCOLOGIST | 2020年 / 25卷 / 02期
关键词
Interpretability; Robustness; Survival data analysis; Test; estimation coherency; Treatment decision making; MEAN SURVIVAL-TIME; HAZARD RATIO;
D O I
10.1634/theoncologist.2019-0464
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:91 / 93
页数:3
相关论文
共 50 条
  • [21] Statistical aspects in adjuvant and neoadjuvant trials for gastrointestinal cancer in 2020: focus on time-to-event endpoints
    Saad, Everardo D.
    Buyse, Marc
    [J]. CURRENT OPINION IN ONCOLOGY, 2020, 32 (04) : 384 - 390
  • [22] Comparing statistical methods in assessing the prognostic effect of biomarker variability on time-to-event clinical outcomes
    Gao, Feng
    Luo, Jingqin
    Liu, Jingxia
    Wan, Fei
    Wang, Guoqiao
    Gordon, Mae
    Xiong, Chengjie
    [J]. BMC MEDICAL RESEARCH METHODOLOGY, 2022, 22 (01)
  • [23] Comparing statistical methods in assessing the prognostic effect of biomarker variability on time-to-event clinical outcomes
    Feng Gao
    Jingqin Luo
    Jingxia Liu
    Fei Wan
    Guoqiao Wang
    Mae Gordon
    Chengjie Xiong
    [J]. BMC Medical Research Methodology, 22
  • [24] A flexible and coherent test/estimation procedure based on restricted mean survival times for censored time-to-event data in randomized clinical trials
    Horiguchi, Miki
    Cronin, Angel M.
    Takeuchi, Masahiro
    Uno, Hajime
    [J]. STATISTICS IN MEDICINE, 2018, 37 (15) : 2307 - 2320
  • [25] Statistical methods to compare functional outcomes in - randomized controlled trials with high mortality
    Colantuoni, Elizabeth
    Scharfstein, Daniel O.
    Wang, Chenguang
    Hashem, Mohamed D.
    Leroux, Andrew
    Needham, Dale M.
    Girard, Timothy D.
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2018, 360 : j5748
  • [26] A menu-driven facility for sample-size calculation in multiarm, multistage randomized controlled trials with time-to-event outcomes: Update
    Bratton, Daniel J.
    Choodari-Oskooei, Babak
    Royston, Patrick
    [J]. STATA JOURNAL, 2015, 15 (02): : 350 - 368
  • [27] Analysis of Time to Event Outcomes in Randomized Controlled Trials by Generalized Additive Models
    Argyropoulos, Christos
    Unruh, Mark L.
    [J]. PLOS ONE, 2015, 10 (04):
  • [28] Design and analysis of cluster randomized trials with time-to-event outcomes under the additive hazards mixed model
    Blaha, Ondrej
    Esserman, Denise
    Li, Fan
    [J]. STATISTICS IN MEDICINE, 2022, 41 (24) : 4860 - 4885
  • [29] Statistical power in parallel group point exposure studies with time-to-event outcomes: an empirical comparison of the performance of randomized controlled trials and the inverse probability of treatment weighting (IPTW) approach
    Peter C. Austin
    Tibor Schuster
    Robert W. Platt
    [J]. BMC Medical Research Methodology, 15
  • [30] Statistical power in parallel group point exposure studies with time-to-event outcomes: an empirical comparison of the performance of randomized controlled trials and the inverse probability of treatment weighting (IPTW) approach
    Austin, Peter C.
    Schuster, Tibor
    Platt, Robert W.
    [J]. BMC MEDICAL RESEARCH METHODOLOGY, 2015, 15